Introduction. Biliary strictures of benign origin are a common problem in clinical practice. The diagnosis and treatment of these strictures are challenging and require a multidisciplinary approach. There are various causes of benign biliary strictures, such as iatrogenic (post-cholecystectomy), inflammatory (primary sclerosing cholangitis), or traumatic (blunt abdominal trauma). Aim. The aim of this study is to evaluate the contemporary diagnostic and treatment modalities of biliary strictures of benign origin at a university surgical center. Material and methods. The integral prospective and retrospective cohort study analyzed the longterm results of biliodigestive reconstructions in 203 patients who underwent the procedure between 1989 and 2015. The patients included in the study were monitored for 2-5 years, taking into account the local anatomic particularities at the time of reconstructive surgery, as well as the remote clinical-evolutionary particularities, using the clinical Terblanche score. Results. The majority of the patients (73.3%) were female, and the mean age was 54.9 years. Individualized reconstructive surgical treatment was performed based on the level of biliary strictures, with a preference for biliodigestive derivations on jejunal loop a la Roux. Treatment for benign biliary strictures, classified according to Bismuth’s classification, included choledoco-jejuno-stomy in 86 (42.4%) cases of type I and II strictures, hepaticojejunostomy in 102 (50.2%) patients with type III strictures, and bihepatico-jejuno-stomy in 15 (7.4%) cases of type IV strictures. Remote results were classified as very good in 123 (60.6±4.41%) cases, good in 39 (19.2±6.31%) cases, relatively satisfactory in 18 (8.9±6.91%) cases, and unsatisfactory in 23 (11.3±6.75%) cases, based on the clinical-evolutive classification. Conclusion. Biliary strictures of benign origin remain a challenging condition for diagnosis and treatment. Hepaticojejunostomy on Roux loop is the preferred surgical option for biliary strictures. An analysis of remote results showed that reconstructive interventions were clinically effective in 88.67% of cases. The success rate of treatment is high, but complications may occur.