Objective: Fragility is a complex geriatric syndrome characterized by decreased vitality and increased vulnerability, affecting up to 25% of the population over 60 y. With the increase of life expectancy and the tendency of demographic aging, an increase in the prevalence of fragile patients is estimated. We need to develop effective methods of prevention, diagnosis and treatment of frailty in order to maintain the autonomy process in the elderly population. A good management of polypathology in elderly can lead to the improvement of the quality of life and decrease of the number of patients with fragility syndrome. It has an increased prevalence and is the main risk factor for falls, invalidity, hospitalization in medical institutions, need for social care or mortality. Aim of the study was assessment of physical and cognitive status in frail elderly patients. Methods: The study included 1158 patients, men - 41.45% and women 58.54%, aged between 65-96 y, the mean being M 71.74±ES 0.17, admitted to the Department of Geriatric Chronic Diseases, from 2015-2017. The standardized geriatric evaluation was applied to all patients in the study. Freid criteria were used to establish the fragility syndrome. Physical status was assessed by Katz and Lawton score, balance and gait evaluation by Tinetti test. Cognitive status was assessed using the MMSE scale. The data obtained were subjected to statistical analysis, StatSoft Statistica 7. Results: The fragility syndrome was established in 27.20% of patients. Fragility was diagnosed more frequently in women - 58.73% of cases. Patients with frailty had lower autonomy and cognitive function (ADL 9.23±0.18; IADL - 10.77±0.24),MMSE - 22.62±0.28. Disorders of walking and balance (Tinetti - 20.43±0.29) but also a higher frequency of fall syndrome 40.3% with traumatic consequences 14.6%, psychological consequences 11.42% and total loss of autonomy post-drop 7.30%. Conclusion: Fragility syndrome is a condition commonly found in the elderly, with ageing a person changes the cognitive and physical state to the one of fragile patient. It has a high prevalence in elderly patients Eastern Europe countries, having a high social impact.