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SM ISO690:2012 RĂZLOG, Tatiana, GROPPA, Liliana, ROTARU, Larisa, SASU, Dorian, GROZA, Costina. Impact of SARS-Cov2 infection on chronic kidney disease. In: New horizons in urology: The 8th congress on urology, dialysis and kidney transplant from Republic of Moldova with international participation, 7-9 iunie 2023, Chişinău. Chişinău: Taicom (Ridgeone Group), 2023, p. 328. ISSN 2558-815X. |
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New horizons in urology 2023 | ||||||
Conferința "New horizons in urology" Chişinău, Moldova, 7-9 iunie 2023 | ||||||
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Introduction. Patients with kidney diseases contracting SARS-CoV2 have an increased degree of severe evolution of the disease. According to studies, most patients who died due to complications of SARS-CoV2 infection had comorbidities, 20% of patients had pre-existing kidney diseases. Aim of study. Determination of the particularities of the evolution of SARS-CoV2 infection in patients with pre-existing kidney diseases. Material and methods. An analysis of articles published in the last 2 years, in the databases PubMed, SCOPUS and HINARI, was performed. The search terms were (in English): "kidney AND SARS-CoV2", "ckd AND covid-19". Results. Most of the studies performed have demonstrated that the most common renal complication in SARS-CoV2 infection is acute kidney injury. The severe form of SARS-CoV2 infection was determined in 25% of people with pre-existing kidney diseases. Worsening of kidney function has been observed in patients with kidney disease who have endured COVID-19. Patients with chronic kidney disease are susceptible to any type of infection in its severe form, due to the immunocompromised state. Uremia causes a state of constant suppression of the immune system, and uremic patients have dysregulation of adaptive immunity to infections. The most common causes of death in patients with CKD associated with SARS-CoV2 infection were cardiovascular complications. Conclusions. All retrospective studies have identified 4 major risk factors for severe SARS-CoV2 infection: cardiovascular disease, hypertension, diabetes mellitus and chronic kidney disease. Compared to the other risk factors (CVD, hypertension, DM), CKD was found to be a major risk factor for death. |
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