The higher education landscape is constantly evolving. Undeniably, different countries practice different approaches, methods and techniques. The USA has got a lot of useful lessons to share in this respect. Being the third biggest country in the world, which is welcoming professionals, researchers, students, immigrants from all over the world, it can show a good example as to how to prepare well-qualified specialists in various fields. American universities constitute the majority of the highest-ranking institutions in the worlds. That is why American higher-education practices and realities are worth considering and following through. It is no wonder the US remains the most popular destination by far for international students, who are drawn to this country because it is home to some of the best universities in the world, which offer great educational diversity for students. It is not possible to encompass the whole range of teaching/learning/researching aspects and experiences that are used in American universities in one article. For this reason, the present study focuses just on some of them, including syllabus development, problem-based learning (PBL), universal design for learning (UDL), cooperative learning, course delivery formats, flipped classroom, educational technology, and experiential learning. To a great extent, the presented issues are based on the authors’ personal academic experience of both studying and working in the USA.