Introduction. Ovarian ischemia is a pathological condition that frequently occurs following torsion of the ovaries. In the case of healthy ovaries exposed to ovarian torsion (OT), it is extremely important to ensure their preservation by detorsion (DTO), as a radical surgical intervention to remove them could lead to hormonal disorders and infertility with a decreased quality of life. The aim of the research was to evaluate the tissue metabolic changes in ovarian torsion after torsion removal in order to highlight the optimal intervention strategies to reduce the negative impact of reperfusion. The study was approved by the Research Ethics Committee. Material and methods. 70 laboratory rats were randomly assigned, by 10, in 7 study groups: control, sham (only laparotomy), OT 3h, OT 3h / DTO 1h, OT 3h / cDTO 1h, OT 3h / DTO 24h, OT 3h / cDTO 24h. cDTO (controlled detorsion) included the opening and closing of the atraumatic ovarian pedicle clip with a 10 seconds interval, for 2 minutes, at the beginning of the reperfusion period. The levels of lactate and malondialdehyde (MDA) were measured in the ovarian homogenates. The statistical analysis was performed using SPSS software. Results. It was determined that ischemia increased lactate by 38%, p=0.006, and MDA by approximately 23%, p<0.001, compared to the control group. After 1 h from cDTO, as well as DTO, the lactate levels were maintained similar to the amount recorded in the group with only OT, p>0.05, and over 24 h in both DTO and cDTO groups, a decrease in the lactate levels were observed, close to the control group, p>0.05. cDTO compared to DTO maintained MDA at the level of the values recorded in the group with only OT, p>0.05. In the groups with DTO the level of MDA was statistically significant higher, compared to both OT and cDTO groups, p<0.001. Conclusion. cDTO has a beneficial effect by reducing the formation of MDA, which is a specific biomarker for oxidative damage induced by the amplification of oxidative stress during the reperfusion period. Further studies with concomitant administration of antioxidants are required.