Objective: Objective of this study was to investigate the potential correlation between hemoglobin levelsand Parkinson’s disease (PD) severity, and to compare them with a control group of healthy individuals. Background: Previous studies have suggested a possible link between anemia and Parkinson’s disease (PD).Some studies found that low hemoglobin (Hb) levels were associated with an increased risk of PD. However,the relationship between Hb levels and PD severity is not well understood. Method: This study included 58 patients with PD (56.9% female, 43.1% male) and 70 healthy controls. Hblevels were measured and compared between different stages of disease severity as measured by the Hoehnand Yahr (H&Y) scale, UPDRS III and between the PD group and the control group. Statistical analysesincluded the Mann-Whitney test, Kruskal-Wallis test, and Spearman’s correlation test. Results: The PD group and control group were homogeneous with respect to age (p=0.9). Hb levels did notdiffer signifi cantly between the different stages of disease severity (p=0.516) or between the PD group andthe control group (p=0.7). Additionally, there was no signifi cant correlation between Hb levels and diseaseseverity as measured by the UPDRS III (r=0.3, p=0.6). Conclusion: These results suggest that Hb level is not signifi cantly correlated with disease severity inpatients with PD. However, further research with larger sample sizes is needed to confi rm these fi ndings andto better understand the relationship between Hb levels and PD. To cite this abstract in AMA style: O. Gavriliuc, L. Rotaru, M. Gavriliuc, A. Caldarov. Correlation between hemoglobin level and diseaseseverity in patients with Parkinson’s disease [abstract]. Mov Disord. 2023; 38 (suppl 1).https://www.mdsabstracts.org/abstract/correlation-between-hemoglobin-level-and-disease-severity-in-patients-with-parkinsons-disease/. Accessed December 4, 2023. MDS Abstracts - https://www.mdsabstracts.org/abstract/correlation-between-hemoglobin-level-and-disease-severity-in-patients-with-parkinsons-disease/