Background: Connective tissue dysplasia observed in a significant proportion of the present population of the Earth and is one of the reasons diseases of multifactorial ethiology. One of the manifestations of the syndrome of connective tissue dysplasia is joint hypermobility. The aim of this work was to study the prevalence of joint hypermobility syndrome based on the criteria for joint hypermobility by R. Beighton among medical students. Material and methods: Hypermobility of joints studied 760 students of medical faculty in using the touchstone by R. Beighton. For each positive test was administered rated 1 point. Results of the study were assessed as follows: 1-2 points the norm, 3-4 - easy hypermobility, 5-8 - hypermobility moderate, 9 - generalized hypermobility. Results: Among young adults, 30% of men and 40% of women have expressed a degree or generalized hypermobility of the joints, which is a manifestation of connective tissue dysplasia syndrome. It was detected the differences in the frequency and severity of connective tissue dysplasia syndrome in boys and girls. Indirectly, on the basis of performance criteria for the distribution of the amount of points R. Beighton is a polygenic nature of inheritance of this syndrome. Conclusions: Among young adults revealed a significant incidence of articular manifestations of connective tissue dysplasia syndrome. Taking into account statistically proven relationship of this syndrome to the development of a number of clinical entities of somatic diseases, as well as the possible development of psychological incoordination, these results suggest an increased probability of health problems in these individuals.