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SM ISO690:2012 HADJIU, Svetlana, BUBUCEA, Rodica, ROBU, Mariana, JELIHOVSCHI, Angela, CHELE, Ecaterina. Aspecte evolutive clinico-imagistice ale encefalopatiilor hipoxic-ischemice perinatale. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2012, nr. 5(13), pp. 369-378. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 5(13) / 2012 / ISSN 1857-1719 | ||||||
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Pag. 369-378 | ||||||
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Twenty-four patients with hypoxic-ischemic encephalopathy were examined with serial magnetic resonance imaging up to 4 years of age. Magnetic resonance imaging studies were performed in the neonatal period, at the fourth month and the fourth year of age, and the findings were compared with the patients’ neurodevelopmental utcome at the fourth year of age. Periventricular signal alterations and deep gray matter involvement were usually evident in the initial magnetic resonance imaging studies, and encephalomalacia, periventricular leukomalacia, and atrophy were the common findings on follow-up magnetic resonance imaging studies. In the patients with hypoxic-ischemic encephalopathy, some correlation between magnetic resonance imaging findings and neurodevelopmental outcome was recognized. The patients with deep gray matter involvement on the initial magnetic resonance imaging had a poor prognosis, and the ones with normal magnetic resonance imaging findings had a favorable neurodevelopmental outcome |
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<?xml version='1.0' encoding='utf-8'?> <resource xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xmlns='http://datacite.org/schema/kernel-3' xsi:schemaLocation='http://datacite.org/schema/kernel-3 http://schema.datacite.org/meta/kernel-3/metadata.xsd'> <creators> <creator> <creatorName>Hadjiu, S.A.</creatorName> <affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation> </creator> <creator> <creatorName>Bubucea, R.</creatorName> <affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation> </creator> <creator> <creatorName>Robu, M.G.</creatorName> <affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation> </creator> <creator> <creatorName>Jelihovschi, A.</creatorName> <affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation> </creator> <creator> <creatorName>Chele, E.</creatorName> </creator> </creators> <titles> <title xml:lang='ro'>Aspecte evolutive clinico-imagistice ale encefalopatiilor hipoxic-ischemice perinatale</title> </titles> <publisher>Instrumentul Bibliometric National</publisher> <publicationYear>2012</publicationYear> <relatedIdentifier relatedIdentifierType='ISSN' relationType='IsPartOf'>1857-1719</relatedIdentifier> <dates> <date dateType='Issued'>2012-11-01</date> </dates> <resourceType resourceTypeGeneral='Text'>Journal article</resourceType> <descriptions> <description xml:lang='en' descriptionType='Abstract'>Twenty-four patients with hypoxic-ischemic encephalopathy were examined with serial magnetic resonance imaging up to 4 years of age. Magnetic resonance imaging studies were performed in the neonatal period, at the fourth month and the fourth year of age, and the findings were compared with the patients’ neurodevelopmental utcome at the fourth year of age. Periventricular signal alterations and deep gray matter involvement were usually evident in the initial magnetic resonance imaging studies, and encephalomalacia, periventricular leukomalacia, and atrophy were the common findings on follow-up magnetic resonance imaging studies. In the patients with hypoxic-ischemic encephalopathy, some correlation between magnetic resonance imaging findings and neurodevelopmental outcome was recognized. The patients with deep gray matter involvement on the initial magnetic resonance imaging had a poor prognosis, and the ones with normal magnetic resonance imaging findings had a favorable neurodevelopmental outcome</description> <description xml:lang='ro' descriptionType='Abstract'>Au fost expuși studiului 34 pacienţi cu encefalopatie hypoxic-ischemică perinatală (EHIP) prin examen clinico-neurologic evolutiv și rezonața magnetică nucleară (RMN) în dinamică. Examenul RMN s-a efectuat în perioada de nou-născut, la vîrsta de 4 luni şi la 4 ani. Au fost comparate rezultatele clinice obținute cu datele RMN. Pe RMN iniţial erau prezente semne de alterare periventriculară cu implicarea profundă a substanţei cenusii. Pe tablourile RMN în dinamică erau commune: encefalomalacia multicistică, leucomalacia periventriculară şi atrofia corticală. S-au apreciat anumite corelaţii între rezultatele RMN şi dezvoltarea neurologică ulterioară a copiilor cu EHIP. Pacienţii cu afectarea profundă a substanţei cenuşii confirmate prin RMN, iniţial, prezentau un prognostic nefavorabil, cei cu rezultate RMN normale aveau o dezvoltare neurologică ulterioar bună. RMN în dinamică, confirmat cu encefalomalacie si leucomalacia periventriculară au fost asociate cu consecințe în dezvoltarea neurologică.</description> </descriptions> <formats> <format>application/pdf</format> </formats> </resource>