Introduction. Skin diseases affect people of all ages and are of major concern due to their association with the human immunodeficiency virus and have been identified as a public health problem. It is estimated that atopic dermatitis affects approximately 230 million people worldwide, which constitutes 3.5%, and the clinical severity of dermatitis, correlates with the patient's perception of quality of life and affects physical ability to work [1]. Purpose of the work. Phytotherapeutic products in the treatment of atopic dermatitis and their administration in terms of chemical compounds and mechanisms of action were evaluated. Material and methods. Scientific publications of skin diseases and vegetal products used in atopic dermatitis were evaluated in terms of their administration (PubMed, ScienceDirect, Scopus, Google Scholar). Phytomedicines were evaluated according to the State Nomenclature of Medicines of the Republic of Moldova [2] and their presence in community pharmacies in Chisinau. Results. The prevalence of the most common skin diseases showed that fungal skin infections (8.92%) ranked first, followed by acne (5.36%), atopic dermatitis (5.48%), alopecia (5.12%) and psoriasis (3.92%), with a higher prevalence for women than for men [3]. For the Republic of Moldova, according to the estimates of the National Bureau of Statistics, for the year 2020 out of 920.1 thousand patients who went to the doctor, 33.7 thousand were detected with skin and subcutaneous tissue pathologies, which constitutes 3.66%. Phytomedicines used in the treatment of eczema account for 1.4% of the number of authorised products included in the State Nomenclature of Medicines, with a presence of 68% in community pharmacies. These include vegetal products and phytomedicines rich in essential oils with anti-inflammatory, antihistamine, antiseptic properties (Marticariae flores, Millefolii herba, Salviae folia), with regenerating vitamins (Calendulae flores, Bidentis herba), containing emollient polyholozides (Althaeae radices, Echinaceae herba, Avenae fructus), anti-inflammatory anthracene derivatives (Aloe arborescens folia, Hyperici herba), astringent tannin substances (Juglandis folia, Querci cortex). Products containing alkaloids (Chelidonii herba, Symphyti radices) should only be used with caution when administered externally. Conclusions. The use of phytomedicines in atopic dermatitis is based both on their long-standing traditional application in vitro and in vivo scientific studies confirming their efficacy and safety.