Until long time the most important way of the benign prostatic hyperplasia (BPH) symptoms treatment was considered the surgical cure consorted by reduced mortality (0,2%) and complications frequency (18%). In connection with this a lot of patients who are recommended the surgical intervention tend to obtain a therapeutically treatment. In our study were included 30 patients with BPH, acute and chronic prostatitis who had no direct indications for surgical intervention. The drug Adenoprosin was administrated in the shape of suppository once a day during 2 month. All the patients were subjected to an investigational algorithm in concordance with the International Consultation on BPH recommendations. The treatment results determined the harmless and the efficiency of the drug treatment, the initiation time, the therapy duration and the multitude necessity of its application. In these patients (96-98%) Adenoprosin exert a fast and an essential improvement of general symptoms and urodinamic parameters in the first 3-4 weeks of administration with there further keeping during 4-6 months after the treatment.