The article presents an overall picture of the latest technological trends altogether referred to as the Fourth Industrial Revolution (Industry 4.0), their i mpact on the education and on the changing structure of the labour market, the demand for prospective skills, as well as emerging policy challenges. In order to prepare graduates for the future life and work done by Industry 4.0, where intelligent robots w ill replace people in certain divisions of activity, education should use relevant information and skills that cannot be replaced with robots. The paper analyzes the main trends in the labor market and formulated conclusions for future systemic approach to education, labor market and major technical and technological changes.