Medicinal plant raw materials and preparations based on them continue to play an important role in the pharmacotherapy of many chronic and acute human diseases. According to the latest studies, herbal medicines make up approximately 25% of the total number of registered medicines on the pharmaceutical market of Ukraine. Phytopreparations have both advantages and disadvantages compared to drugs based on synthetic substances. The main advantages of herbal preparations include a wide spectrum of action, low level of toxicity, availability. The main disadvantages are the lack of a proven level of effectiveness through clinical studies for the majority of "traditional" and long-standing herbal preparations, difficulties in standardization and unpredictability in side effects. However, despite the listed disadvantages, more and more people around the world believe that herbal remedies are better than synthetic remedies. A detailed study of the phytochemical composition, optimization of the extraction process, and pharmacological properties of representatives of already known medicinal plants is necessary for the creation of new herbal preparations. Representatives of medicinal plants include the fruit of the gourd family Momordica charantia, which is used in folk medicine in many countries of the world, but has not been thoroughly studied. It is known that the list of active substances of Momordica charantia includes: vitamins A, B, C, F; minerals – potassium, calcium, silicon, selenium, phosphorus; folic, nicotinic, pantothenic, ascorbic acid; a large number of amino acids; saponins; alkaloids; dietary fiber; phenols, resins, fatty oils; carbohydrates and many other valuable substances. Thus, it is expedient to study Momordica charantia and create, on the basis of the conducted phytochemical studies, a phytopreparation based on Momordica charantia extract for introduction into therapeutic practice. It was analyzed that when comparing the ratio of chlorophyll a and b (1.547 mg/l in unripe and 0.381 mg/l in ripe fruits), as well as the total amount of chlorophyll (a and b) to carotenoids (5.363 mg/l in unripe and 2.343 mg/l l in ripe fruits), testify to the effectiveness of using 70% ethanol as a solvent, which is able to ensure a high degree of extraction of the target product from medicinal plant raw materials (Table). Determining the moisture content in samples of Momordica charantia plant material and studying the concentration of accumulation in extracts of magnesium complexes of tetrapyrroles of the porphyrin structure allows to establish the total content of chlorophyll (a and c) and carotenoids (mg/g of dry material) directly in the studied samples of Momordica charantia. The ratio of pigments in fruits Momordica charantia Concentration of water-ethanol mixture Unripe fruits Ripe fruits a/b (a+b)/carotenoids a/b (a+b)/carotenoids 30 % 0,377±0,012 0,711±0,07 0,150 0,636 50 % 0,372±0,007 1,177±0,011 0,111 1,103 70 % 1,547±0,004 5,363±0,023 0,381 2,343 The research results indicate that the largest amount among the studied pigments in the unripe fruits of Momordica charantia is chlorophyll a (3.98 mg/g of dry raw material). The content of chlorophyll b and carotenoids was 0.54 and 0.34 mg/g of dry raw material, respectively. The content of polyphenolic compounds (PFS) was determined spectrophotometrically according to the Folin-Chocalteo method in terms of gallic acid. The study of the concentration of phenolic compounds was carried out at different concentrations of the solvent and the ratio of raw materials to the solvent. According to the results of the analysis, it was established that the largest amount of phenolic compounds was observed in unripe fruits of Momordica charantia under the conditions of extraction with a 70% water-ethanol mixture. The content of phenols was 1.2 mg/g ofdry raw material. During the extraction of ripe fruits of momordica, the highest yield of active compounds was 0.9 mg/g of dry raw material When extracting plant raw materials at different ratios, a linear dependence of the release of active substances into the solvent system with an increase in the hydromodulus ratio was noted. It should be noted that among the selected parameters, the highest yield of phenolic compounds was observed at a ratio of raw material to solvent of 1:10 in a sample of unripe fruits of the motherwort. The results of the study of the quantitative content of polyphenolic compounds in extracts from the fruits of Momordica charantia are presented in fig. Fig. The content of polyphenolic compounds in the fruits of Momordica charantia at different ratios of raw materials to extract Increasing the hydromodulus from 1:5 to 1:10 in samples of extract from ripe fruits, did not increase the concentration of polyphenolic compounds in the extract, the total content of polyphenols was on average 0.56 mg/g of dry raw material. According to our research, it is shown that the most optimal hydromodule for mature fruits is the raw material to extractant ratio of 1:5, and further increase is not advisable and economically beneficial. It was established that the highest total content of polyphenolic compounds was observed in the unripe fruits of Momordica charantia 1.2 ± 0.2 mg/g of dry raw material under the conditions of extraction with 70% ethanol at a ratio of raw material to solvent of 1:10. The highest content of polyphenolic compounds in ripe fruits was 0.9 ± 0.1 mg/g of dry raw material under the conditions of extraction with 50% ethanol at a ratio of medicinal plant raw material to solvent of 1:5.