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SM ISO690:2012 ZAHARIE, Gabriela, BLAGA, Ligia, POPA, Monica, KUDOR-SZABADI, Liana, SCHMIDT, Nadia, PANGA, Gabriela, ONA, D.. Insuficienţa renală la nou-născutul cu asfixie perinatală. In: Buletin de Perinatologie, 2008, nr. 2(38), pp. 99-101. ISSN 1810-5289. |
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Buletin de Perinatologie | ||||||
Numărul 2(38) / 2008 / ISSN 1810-5289 | ||||||
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Pag. 99-101 | ||||||
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Kidneys are extremly sensitive to hypoxemia, renal failure develops during the first 24 hours from the asphyxic injury and if this prolongs it may lead to acute tubular necrosis. It is important an early diagnosis of renal failure in a newborn with asphyxia to initiate a proper therapeutic conduct. Hypothesis. This study aims to determine incidence of renal failure in asphyxic newborn and correlate renal failure with Apgar score and neurologic injury severity. Material and method. We made a retrospective study over 18 months on newborns from Neonatology Department of Obstetrics and Gynecology I Clinic Cluj-Napoca.Study group consisted of newborns diagnosed with perinatal asphyxia according to criteria established by American Association of Pediatrics.
Results. Study group:38 newborns diagnosed with perinatal asphyxia(1.15%).21 were term and 17 were preterm newborns;birth weight average was 3269.04±599.12 grams and 1987.64±710.11, with no statistically significance on perinatal asphyxia severity(p=0.890). Renal injury, consequnce of hypoxic insult was 50% in preterm and 55% in term newborns,with no statistic differences between the two groups.Oliguria occured in 58.3% of preterm and 35% of term newborns and anuria in 10% of term and 16.7% of preterm newborns.Creatinine serum correlated significantly with mortality incidence (r=0.60) and neurologic injury severity (p=0.002). Conclusions. Renal injury incidence in perinatal asphyxia is 50% for preterm and 55% for term newborns. Degree of renal injury distinguished by creatinine value was significantly correlated to seizures and mortality rate. |
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Cuvinte-cheie insuficienta renala, asfixie, mortalitate |
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