Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
262 0 |
Căutarea după subiecte similare conform CZU |
616.136.46-005.6-06-07 (1) |
Patologia sistemului circulator, a vaselor sanguine. Tulburări cardiovasculare (978) |
SM ISO690:2012 CRĂCIUN, Ion. The diagnostic role of serum lactate in acute mesenteric ischemia. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 323. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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CZU: 616.136.46-005.6-06-07 | ||||||
Pag. 323-323 | ||||||
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Background. Early diagnosis of acute mesenteric ischemia (AMI), until intestinal necrosis and peritonitis, is the main factor that ensures the survival of patients. L-lactate is a simple test of anaerobic glycolysis, and the particularity of its metabolism in AMI has been studied for a long time, in experimental and clinical research. Objective. Assessment of the informativeness of serum lactate in AMI. Materials and Methods. In this study, this indicator was tested in 45 consecutive patients with acute mesenteric ischemia. Results. An increase in blood lactate levels was found in 10 (22.2%) patients with AMI with a range of 2.3 to 10.7 mmol/L, with a mean value of 3.9 ± 0.8 mmol/L (95% CI: 2.17–5.67). In arterial AMI, the level of L-lactate is statistically (p <0.05) higher than in the venous one. It was established that the level of L-lactate is higher in arterial embolism than in arterial thrombosis, but statistically it is untrue (p = 0.8409) respectively 2.52 ± 0.4 vs 2.1 ± 0.1 mmol/L. When the small intestine is involved in ischemia only, the L-lactate level is lower than when the small and large intestine is involved at the same time, and is respectively 1.7 - 0.2 (95% CI: 1.43–2.16) vs 3.1 ± 0.7 (95% CI: 1.51–4.76) mmol/L, with a statistical difference (p = 0.0540). A statistically difference (p < 0.01) of this indicator was established in the sectoral (resectable) and total (unresectable) IMA which constituted respectively - 2.1 ± 0.4 (95% CI: 1.41–2.86) vs 3.5 ± 0.2 (95% CI: 2.73–4.31) mmol/L. Conclusion. L-lactate may be used as an indicator for the diagnosis of AMI. The diagnostic value increases especially by associating this marker with other serological markers. |
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Cuvinte-cheie L-lactate, acute mesenteric ischemia, L–lactat, ischemia mezentericã acutã |
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