Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
199 3 |
Ultima descărcare din IBN: 2023-08-26 03:24 |
Căutarea după subiecte similare conform CZU |
616-089.5 (18) |
Patologie. Medicină clinică (6964) |
SM ISO690:2012 MANASTÂRSCHI, Stanislav, IAPĂSCURTĂ, Victor. System dynamics models for clinical anesthesia (on the example of propofol). In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 314. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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CZU: 616-089.5 | ||||||
Pag. 314-314 | ||||||
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Background. Systemic dynamics models (MSDs) describing the pharmacokinetics and pharmacodynamics of the anesthetic have been used for some time. Most of these models are standard models, which, at best, can be adjusted to a specific clinical case / patient only partially. Objective of the study. Presentation of a prototype SDM for propofol that allows the adjustment of the model for a specific patient. Material and Methods. The NetLogo programming language is used to create MSDs and standard data on the pharmacokinetics and pharmacodynamics of propofol. Results. Using the NetLogo programming language, an MSD was created that allows personalization of the model for a specific patient, using patient data (body mass, height, heart rate, etc.) that can facilitate the choice of the optimal dose of propofol (continuous bolus and infusion) for the patient. dat. The model is available on the platform: http://modelingcommons. org/ Conclusion. The proposed model after its clinical calibration could improve the management of intravenous anesthesia with propofol in a specific patient by customizing the model for that patient. |
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Cuvinte-cheie general intravenous anesthesia, propofol, dynamic systemic model, customized model, anestezie generală intravenoasă, propofol, model sistemic dinamic, model personalizat |
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