Conţinutul numărului revistei |
Articolul precedent |
Articolul urmator |
276 3 |
Ultima descărcare din IBN: 2024-01-14 16:18 |
Căutarea după subiecte similare conform CZU |
616.728.3-007.248+577.161.2 (1) |
Patologia organelor de locomoţie. Sistemul osos şi locomotor (469) |
Bazele materiale ale vieții. Biochimie. Biologie moleculară. Biofizică (664) |
SM ISO690:2012 CURCHI, Mirela, DESEATNICOVA, Elena, AGACHI, Svetlana, GROPPA, Liliana. Vitamin D deficiency and pain in knee osteoarthritis. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 195. ISSN 2345-1467. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
|
||||||
CZU: 616.728.3-007.248+577.161.2 | ||||||
Pag. 195-195 | ||||||
|
||||||
Descarcă PDF | ||||||
Rezumat | ||||||
Introduction. Vitamin D has many immunomodulatory properties, which support its anti-inflammatory role. Low levels of vitamin D 25OH in serum are commonly detected in patients with rheumatic diseases. Objective of the study. To appreciate the effects of vitamin D supplementation on the symptoms of osteoarthrosis of the knee (OA) and the level of pain in these patients. Materials and methods. Observational, case-control study 64 patients divided into 2 groups: group 1 - 38 patients with OA with vitamin D deficiency and group 2 - 26 with OA with optimal vitamin D level, (average age of patients 64, 2 ± 1,4 [71-56] years), women 81,5%, men 18,5%. Indices used: body mass index (BMI), ESR, PCR, 25 OH Vitamin D, VAS - visual analog scale. Statistics: t-Student and Pearson r. Results. BMI was 29.13 (95%CI 32.04-26.02) vs. 26.46 (95%CI 28.93-24.40) kg/m², p < 0.05. The level of 25(OH) vitamin D was 11.3 ± 4.4 (95%CI 5.84 - 25.21) ng/ml vs. 32.63 ± 6.4 (95% CI 58.3 30.29), p < 0.05. Vitamin D insufficiency <10 ng/mL of the total patients was 59.3%. Patients of both sexes did not have significant differences between vitamin D levels (17.01±5.15 ng/ml) and (17.74 ± 4.03 ng/ml) (p = 0.862). PCR and ESR values were within the normal range, and pain values after VAS were higher than 5.5 ± 0.4 (95% CI 8.323.08) vs. 3.8 ± 0.4 (95% CI 7.84-3.00) in group 1. A weak positive correlation between the degree of pain after VAS and vitamin D deficiency r = 0.302, p = 0.042 Conclusion. Low levels of vitamin D have been a common cause of more intensive pain in patients with OA of the knee. Monitoring and correction of vitamin D levels in the case of OA of the knee may be recommended in the management of these patients. |
||||||
Cuvinte-cheie 25(OH)vitamin D, osteoarthritis of the knee, VAS, 25(OH)vitamina D, osteoartroza genunchiului, vas |
||||||
|