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Articolul precedent |
Articolul urmator |
197 4 |
Ultima descărcare din IBN: 2024-01-29 21:16 |
Căutarea după subiecte similare conform CZU |
616.24-002-02 (7) |
Patologia sistemului respirator. Tulburări ale organelor de respiraţie (757) |
SM ISO690:2012 SCUTARU, Eugenia, BOTNARU, Victor, RUSU, Doina. Assessment of pneumonia in immunocompromised hosts. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 166. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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CZU: 616.24-002-02 | ||||||
Pag. 166-166 | ||||||
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Rezumat | ||||||
Background. Immunocompromised hosts are vulnerable to pulmonary infections from a broad array of pathogens. The diversity of causes, degree of immunosuppression, and the wide spectrum of infectious complications with atypical manifestations, often lead to delayed diagnosis of pneumonia. Aim. To present clinical, imaging, bacteriological and predictive aspects in immunocompromised patients with pneumonia. Materials and methods. The clinical, paraclinical, and imaging data of 71 hospitalized immunocompromised patients with pneumonia. Results. The mean age was 52 years (range 25-80 years). Among the causes of immunocompromise were highlighted: 37 patients with HIV infection, all in the AIDS stage, with a CD4 count below 500 cells/μl, including 60% (21/35) cases with CD4 value below 100 cells/μl; neutropenia in 25 patients with chemotherapy and 9 patients with systemic corticotherapy. The severe evolution of pneumonia was in the majority of cases - 62% (44/71), of moderate severity in 35% (25/71), and mild in 3% (2/71). Death from pneumonia with a severe course occurred in 32% (14/44) cases. No significant correlation was recorded between the severity of pneumonia and predictive scores CURB-65 and CRB-65. The cause of pneumonia was confirmed in 73% of cases (53/71), with the pathogens having a different frequency: viruses 25%, fungi 22.5%, and bacteria 15.5%. Mixed infections were determined in 11% of cases. Conclusion. The broad etiological spectrum includes fungi, bacteria, but also viruses in the context of the SARS-Cov2 pandemic. Pneumonia in a compromised host is often associated with a complicated course, difficult differential diagnosis, delayed resolution, and a high death rate |
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Cuvinte-cheie pneumonia, Immunocompromised host, pneumonie, gazdă imunocompromisă |
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