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Ultima descărcare din IBN: 2024-01-13 21:58 |
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575.113+616-036 (1) |
Genetică generală. Citogenetică generală (427) |
Patologie. Medicină clinică (6964) |
SM ISO690:2012 COȘPORMAC, Mihaela, LUPUŞOR, Adrian, VOVC, Victor. Retinohipotalamic tract and the circadian rhythm. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 52. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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Background. An essential function of the retina is the synchronization of the circadian rhythm based on photic stimuli, which is achieved by joining the transmissions from the retinal ganglion layer in the hypothalamic pathways, light being fundamental in synchronizing body functions with the environment. Objective of the study. Explanation of the neural mechanisms and pathways by which the retina modulates circadian rhythms. Material and Methods. Articles from the search engines PubMed, Google Scholar, Research Gate and HINARI published between 2000-2021 were used. Results. The retinohypothalamic tract (RHT) is a photic neuronal pathway involved in the regulation of circadian rhythm, an essential role being played by ganglion cells with intrinsic photosensitivity. Due to the direct afferents of the optic nerve to the suprachiasmatic nucleus, RHT is responsible for non-image photoreception. In addition to the intrinsically modulated photosensitivity of melanopsin, the ganglion layer receives afferents from cones and rods, providing photic information to the higher centres responsible for circadian hormonal and behavioural changes. There are also two-way relationships between circadian rhythm disorders and retinal disorders. Conclusion. The influence of the retinal neural pathways has an indisputable influence on the circadian rhythm, which would serve as a possible explanation for the correlation between circadian rhythm disorders and retinal pathologies. |
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Cuvinte-cheie Retinohypothalamic tract, circadian rhythm, ganglion cells, tract retinohipotalamic, ritm circadian, celule ganglionare |
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