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Patologia sistemului respirator. Tulburări ale organelor de respiraţie (757) |
Neurologie. Neuropatologie. Sistem nervos (971) |
SM ISO690:2012 BUBUIOC, Ana-Maria, CEBANOVA, Irina, COJOCARU, Lidia, ODAINIC, Olesea, ARION, Marian. Rhino-orbito-cerebral mucormycosis: clinical case report. In: Revista de Ştiinţe ale Sănătăţii din Moldova, 2022, nr. 3 An.1(29), p. 262. ISSN 2345-1467. |
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Revista de Ştiinţe ale Sănătăţii din Moldova | ||||||
Numărul 3 An.1(29) / 2022 / ISSN 2345-1467 | ||||||
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Pag. 262-262 | ||||||
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Background. Mucormycosis is an opportunistic infection with a high lethal potential. The COVID-19 pandemic catalyzed an explosion of rhino-orbito-cerebral mucormycosis (ROCM) reported worldwide. Other cases of ROCM have not been published in the Republic of Moldova yet. Objective of the study. We present a case of ROCM complicated with the invasion of the cerebral venous system and the internal carotid artery (ICA). Material and Methods. The diagnosis was confirmed clinically, through neuroimaging: computed tomography (CT), magnetic resonance imaging (MRI) and morphopathologically. The literature review was conducted based on the particularities of the case. Results. A 68-year-old patient with diabetes mellitus was hospitalized with headache, right exophthalmia, ptosis, chemosis, facial edema - developed post-SARS-CoV-2. Neurological exam revealed ophthalmoplegia and amaurosis, positive meningeal signs. Cerebrospinal fluid exam was consistent with meningitis. Brain MRI showed pansinusitis. Angio-CT revealed thrombi in the ICA and venous sinuses and air in the right ophthalmic vein. Antibacterial, anticoagulant and surgical treatment was administered. Morphopathological examination confirmed mucormycosis. Although treatment with amphotericin B was initiated, the patient died on the 41st day of the disease. Conclusions. Simultaneous arterial and venous cerebral thrombosis in post-COVID-19 patients with diabetes mellitus may suggest ROCM. Mucormycosis could promote an anaerobic infection leading to an air embolism of the neighboring cerebral sinuses and veins. |
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Cuvinte-cheie mucormycosis, SARS-CoV-2, diabetes mellitus, thrombosis, mucormicoza, SARS-CoV-2, diabet zaharat, tromboză |
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