Facile synthesis of hexahydropyrazino[2,3-e]pyrazines from 3-aminomethyl-1,2,4-triazoles

Khomenko Dmytro; Doroschuk Roman O.; Trachevskii Volodymyr; Shova Sergiu; Lampeka Rostyslav

Conţinutul numărului revistei

Articolul precedent

Articolul urmator

232

SM ISO690:2012

KHOMENKO, Dmytro, DOROSCHUK, Roman O., TRACHEVSKII, Volodymyr, SHOVA, Sergiu, LAMPEKA, Rostyslav. Facile synthesis of hexahydropyrazino[2,3-e]pyrazines from 3-aminomethyl-1,2,4-triazoles. In: Tetrahedron, 2016, nr. 9(57), pp. 990-992. ISSN 0040-4020. DOI: https://doi.org/10.1016/j.tetlet.2016.01.068

EXPORT metadate:
Google Scholar
Crossref
CERIF

DataCite
Dublin Core

Tetrahedron

Numărul 9(57) / 2016 / ISSN 0040-4020 /ISSNe 1464-5416

Facile synthesis of hexahydropyrazino[2,3-e]pyrazines from 3-aminomethyl-1,2,4-triazoles

DOI:https://doi.org/10.1016/j.tetlet.2016.01.068

Pag. 990-992

Khomenko Dmytro¹, Doroschuk Roman O.¹, Trachevskii Volodymyr², Shova Sergiu³, Lampeka Rostyslav¹

¹ Taras Shevchenko National University of Kyiv,
² Институт металлофизики им. Г.В. Курдюмова НАН Украины,
³ Institute of Chemistry of the Academy of Sciences of Moldova

Disponibil în IBN: 17 noiembrie 2022

Rezumat

The cyclocondensation of aminomethyl-1,2,4-triazoles and glyoxal gives hexahydropyrazino[2,3-e]pyrazines in good yields. ¹H and ¹³C NMR spectra of the title compounds are described and the molecular structure of 4a,5,6,10a,11,12-hexahydro-(4aR,10aR)-[1,2,4]triazolo[1,5-a][1,2,4]triazolo[1′,5′:1,6]pyrazino[2,3-e]pyrazine was established by single crystal X-ray analysis.

Cuvinte-cheie
1, 2, 4-triazole, amino acid, Conformationally rigid, cyclization, Hexahydropyrazino[2,3-e]pyrazine