Introduction: The inflammatory process gains an important role in recent years in the development of atherosclerosis, atherosclerotic plaque destabilization and incidence of cardiovascular events after coronary angioplasty . The Coronary artery stent implantation triggers an inflammatory response both locally and generally, and elevated indexes of high sensitive Creactive protein serum (hs-CRP) is associated with an increased risk of cardiovascular events amongst these patients. Objective: To determine the role of the increased preprocedural hs-CRP as a predictor of cardiovascular events (periprocedural and remote myocardial infarction, stroke, death and unstable angina) in patients undergoing coronary angioplasty with stent implantation. Material &methods: The study was conducted on 100 patients with stable angina pectoris (74 men and 26 women with an average age of 57,9 ± 0,8 years) who underwent percutaneous coronary intervention (PCI) with stent implantation: 42 patients received metallic stents and 58 received pharmacologically active stents. Patients were divided into two groups: 25 patients with cardiovascular events post-PCI and 75 patients without cardiovascular events post-PCI. The hs-CRP level was registered before the procedure, 72 hours after the procedure, in 1, 3, 6 and 12 months after coronary angioplasty with stent implantation. Results: The preprocedural values of hs-CRP were statistically significantly higher in patients with cardiovascular events comparing to patients without cardiovascular events: 7,72±1,2 vs 4,27±0,5 mg/l (p<0,05) , and after 72 hours, in 1, 3 and 6 months after the procedure no statistically significant difference was registered between groups: 11,68±1,4 vs 8,63±0,9 mg/l (p>0,05); 6,82±1,3 vs 4,95±0,5 mg/l (p>0,05); 5,04±0,9 vs 4,71±0,9 mg/l (p>0,05) and 5,69±1,1 vs 4,16±0,5 mg/l (p>0,05), respectively. After 12 months after the coronary angioplasty hs-CRP level was statistically significantly higher in patients with cardiovascular events comparing to patients without cardiovascular events: 6,44±1,2 vs 3,88±0,6 mg/l (p<0,05). Conclusions: The preprocedural serum level of hsCRP can be considered as predictor of cardiovascular events in patients undergoing the coronary revascularization procedure with stent implantation.