Useful mineral deposits comprise three groups: combustible, metalliferous, nonmetalliferous. The first two groups exist in very small quantities and their role in the sustainable development of the region is minimal. Of interest for sustainable development is the group of non-metals that are made up of different rocks as building materials. Depending on the provision of the population with resources of useful mineral substances of the Northern Development Region, the districts of Soroca, Rascani, Edinet and Floresti are highlighted. The deposits (quarries and mines) of clays, sandy and clayey clays, construction sands and pebbles, limestone and crude limestone, sandstone, gypsum and tripoli are taken to the current record. The number of exploitations of useful mineral substances exists in 8 of the 12 administrative-territorial units, with some concentrations in Soroca and Rascani districts. RD Nord takes precedence over the size of the areas of the limestone mining companies and the areas of the mining operations in operation. At the same time, better quality deposits are extracted, lower quality deposits are neglected. Over the last few decades, huge volumes of production waste have accumulated. In sandstone quarries, the volume of production waste is lower because the extracted material is used almost entirely. Certain environmental problems create the large volume of rubble (limestone flour) accumulated near the quarry. As a result of mining, there is a change in the use of cultivated land, pastures, areas occupied by perennial crops, those covered with forest vegetation by reducing their areas.