Pathologic modifications caused by renal osteodistrophy are various and are diagnosed both in bones and joints as well as in other organs. Clinical examination in such cases should be supplemented by x ray investigation, that helps to determine the character and severity of phosphorus and calcium metabolism disturbances. The large majority of patients show simultaneous development of osteosclerotic and osteopenic foci in different bones, which are relatively frequently associated with calcium deposits formation in soft tissues, internal organs and vascular wall.