Conservative treatment occupies new positions in the therapy of BPH. This is due to several factors, including the increasing number of elderly patients and increasing of their associated diseases (60-90%), which does not allow radical treatment. Efficacy of conservative treatment is already proven by many clinical investigations, which induces an increased popularity of this method of treatment among urologists. The purpose of conservative treatment is not only to defer surgery in time, but is to obtain a high effect of sclerosis of prostate adenoma, and thereby cancellation of the surgery. Currently, pharmaceutical companies come with new and new groups of drugs, most effective in the treatment of BPH. One direction of future therapy in the treatment of BPH is bio-regulatory therapy with suppositories “Adenoprosin”, which is used successfully in the pharmacological treatment of prostate adenoma complicated with inflammatory processes such as acute and chronic prostatitis.