Introducere: Colangiocarcinomul perihilar (tumora Klatskin) reprezinta o afectiune canceroasa a bifurcatiei arborelui biliar, ce se manifesta prin aparitia timpurie a sindromului de icter mecanic. In pofida acestui fapt, majoritatea bolnavilor la momentul diagnosticarii prezinta o forma local avansata a tumorii, cu invazia structurilor anatomice invecinate, fapt ce indica efectuarea operatiei paliative, cu scop de solutionare doar a sindromului de icter mecanic. Pentru un tratament definitiv al bonavului cu tumora Klatskin se impune ablatia tumorii cu refacerea continuitatii arborelui biliar. Supravietuirea bolnavilor cu tumora Klatskin dupa tratamentul chirurgical radical este relativ mica, alcatuind o rata de 65% la un an postoperator, 58% la doi ani si 31,9% la cinci ani. Cazul clinic: O pacienta de 47 ani cu un tablou clinic de icter mecanic. Diagnosticul de tumora Klatskin, Bismuth-Corlette IIIB este stabilit in baza ecografiei, MRCP si a parametrilor biochimici sanguini. Operatia: Rezectia de colangiocarcinom hilar cu hepatectomie partiala (segmente I, II, III, IV a ficatului), rezectie tangentiala de vena porta cu plastia ei, hepaticojejunostomie pe ansa Roux cu drenarea cailor biliare tip Voelker. Evolutie postoperatorie favorabila cu externare la a 30-a zi postoperator. Cazul clinic prezentat releva supravietuirea pacientei dupa o operatie radicala in caz de colangiocarcinom hilar mai mult de doi ani si sase luni pina in momentul actual. Concluzii: diagnosticul de tumoare Klatskin se bazeaza pe examinarile ecografice, MRCP æi a rezultatelor analizelor biochimice ale sangelui; singura optiune de prelungire a vietii bolnavului cu colangiocarcinom hilar este operatia radicala de ablatie completa a tumorii cu refacerea continuitatii arborelui biliar.
Introduction: Perihilar cholangiocarcinoma (Klatskin tumor) is a malign tumor arising from the extrahepatic bile duct bifurcation, which is manifested by early appearance of mechanical jaundice syndrome. Despite this, most patients at the time of diagnosis present a locally advanced tumor with the invasion of neighbouring anatomical structures, that serves as an indication for palliative surgery, solving just the syndrome of mechanical jaundice. For definitive treatment of patient with Klatskin tumor, the ablation of tumour with bile duct reconstruction is required. The survival of the patients after definitive surgery for Klatskin tumor are relative low: 65% after one year post surgery, 58% after two years and 31.9% after five years. Clinical case: Patient B., a 47-year-old women, with presentation of mechanical jaundice. Diagnosis of Klatskin tumor, Bismuth-Corlette IIIB was confirmed by ultrasound, MRCP and biochemistry analysis of blood. Performed surgery: Resection of hilar cholangiocarcinoma with partial hepat-ectomy (I, II, III, IV liver segments), tangential resection of portal vein with its stitching and Roux-Y hepatico-jejunostomy with Voelker drainage of bile duct. Favourable post-operative evolution with discharging from the hospital in 30 days after surgery. The presented case reveals the survival of one patient after radical surgery for Klatskin tumor more than two years and six mounts to date. Conclusions: The diagnosis of Klatskin tumor is based on the ultrasound, MRCP and biochemistry analysis of blood; the only option to extend the life of the patient with hilar cholangiocarcinoma is the radical surgery - complete ablation of the tumor with restoration of biliary tree continuity.
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