The topic of this presentation is to present a project of Student‗s Grant Competition of the Faculty of Health Studies, University of Pardubice, Czech republic. It is aimed at joining two areas in nursing, hygiene and epidemiology. The project generally focuses on protection and promotion of health, enhancement of life quality and lengthening of human lifetime. The research is in particular focused on the occurrence of infections associated with health care. The danger lies in the lengthening of the treatment period which increases the costs of health care. The main aim of the project is to map current nursing practices in prevention of infections. The other partial targets of the project are: - To map the incidence of chosen infections - To detect the most common mistakes - To evaluate the compliance between the methodical instructions and a real situation - To appraise the knowledge of nurses and other nursing staff - To prepare a study material - To make visual supplements to the methodical manual The research will be realized in Pardubice region hospitals and in other chosen inpatient medical facilities in the Czech Republic. To achieve the set targets there will be used a combination of several research tools. To map the incidence of the infections associated with health care there will be chosen retrospective and prospective research survey methods done by means of studying materials The following research methods will be used to detect the most frequent mistakes causing the spread of infections associated with health care and to assess the compliance between the methodical instructions of the chosen medical facility and the real situation: covert observation, checklist audit. The contribution of the project will be clinical (improvement of the quality of care) and educational (scientific publication for students, educational material for paramedical staff).