Revising the definition of extensively drug-resistant tuberculosis
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LANGE, Christoph G., CHESOV, Dumitru, FURIN, Jennifer Joan, UDWADIA, Zarir Farokh, DHEDA, Keertan U.J.. Revising the definition of extensively drug-resistant tuberculosis. In: The Lancet Respiratory Medicine, 2018, vol. 6, pp. 893-895. ISSN 2213-2600. DOI: https://doi.org/10.1016/S2213-2600(18)30428-4
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The Lancet Respiratory Medicine
Volumul 6 / 2018 / ISSN 2213-2600

Revising the definition of extensively drug-resistant tuberculosis

DOI:https://doi.org/10.1016/S2213-2600(18)30428-4

Pag. 893-895

Lange Christoph G.1, Chesov Dumitru12, Furin Jennifer Joan3, Udwadia Zarir Farokh4, Dheda Keertan U.J.5
 
1 German Centre for Infection Research (DZIF), Partner Site Hamburg-Luebeck-Borstel-Riems,
2 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
3 Harvard Medical School, Boston,
4 Hinduja Hospital and Research Centre, Mumbai,
5 University of Cape Town, Cape Town
 
 
Disponibil în IBN: 6 decembrie 2021


Rezumat

WHO estimated that in 2017, 460 000 people developed multidrug-resistant (MDR) tuberculosis, defined by bacillary resistance to rifampicin and isoniazid, the two most effective first-line anti-TB drugs. Approximately 8·5% of MDR tuberculosis isolates had additional drug resistance to at least one fluoroquinolone and one of the second-line injectable drugs amikacin, capreomycin and/or kanamycin, which together define extensively-drug resistant (XDR) tuberculosis.

Cuvinte-cheie
Antitubercular Agents, extensively drug-resistant tuberculosis, Global Health, Humans