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<creators>
<creator>
<creatorName>Butnaru, M.</creatorName>
<affiliation>Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“, Moldova, Republica</affiliation>
</creator>
</creators>
<titles>
<title xml:lang='ro'>Ulcere corneene: metode de tratament</title>
</titles>
<publisher>Instrumentul Bibliometric National</publisher>
<publicationYear>2015</publicationYear>
<relatedIdentifier relatedIdentifierType='ISBN' relationType='IsPartOf'>978-9975-3168-4-2</relatedIdentifier>
<subjects>
<subject>cornee</subject>
<subject>leucom</subject>
<subject>epitelizare</subject>
<subject>cheratoplastie</subject>
<subject>cornea</subject>
<subject>corneal leucom</subject>
<subject>epithelialization</subject>
<subject>Keratoplasty</subject>
</subjects>
<dates>
<date dateType='Issued'>2015</date>
</dates>
<resourceType resourceTypeGeneral='Text'>Conference Paper</resourceType>
<descriptions>
<description xml:lang='ro' descriptionType='Abstract'><p>Introducere. Conform datelor OMS, orbirea corneana ocupă locul trei. Ponderea ulcerelor corneene constituie 6-23,2%. Scopul lucrării. Studierea etiopatogenezei şi a eficacității tratamentului conservator şi chirurgical al ulcerului corneean. Material şi metode. Studiu retrospectiv, 31 pacienți, v&acirc;rsta 15-75 ani. Şaptesprezece (54,83%) s-au tratat conservativ (antibacteriene, antiinflamatoare, desensibilizante, preparate ce ameliorează trofica şi regenerarea, crioaplicația şi introducerea lentilelor curative), 14 (45,17%) chirurgical (42,85% acoperirea UC cu autoconjunctivă; 14,29% acoperirea UC cu grefă liberă a mucoasei buzei; 28,57% cheratoplastie tectonică şi curativă; 14,29% blefarorafie). Rezultate. La 61,29% ulcerele au fost &icirc;n centrul corneei sau paracentral, la 38,61% la periferie, dimensiunile zonei infiltrate (mm) 4,3&plusmn;2,2. Evoluția &icirc;n urma tratamentului conservativ şi chirurgical a fost: epitelizarea completă a defectului cornean &icirc;n 11,6&plusmn;0,16 zile &icirc;n cazul tratamentului conservativ şi respectiv 8,9&plusmn;0,11 &icirc;n cel chirurgical. Resorbția hipopionului 5,8&plusmn;0,16 şi 6,1&plusmn;0,15 zile. Dispariția edemului perifocal şi a infiltrării stromei 8,7&plusmn;0,14 şi 8,7&plusmn;0,12. Rezolvarea inflamației &icirc;n 14,7&plusmn;0,14 şi 12,1&plusmn;0,14 zile. Sindromul cornean a diminuat &icirc;n 12,2&plusmn;0,9 şi respectiv 6,1&plusmn;0,1, dispariția sindromului dolor &icirc;n 12,8&plusmn;1,1 şi 5,1&plusmn;0,12 zile. AV inițială a pacienților tratați conservator a fost 0,05&plusmn;0,01 şi respectiv 0,03&plusmn;0,02 a celor ce au fost tratați chirurgical. La finele tratamentului, AV a atins media 0,2&plusmn;0,01 &icirc;n tratamentul conservativ şi 0,3&plusmn;0,12 &icirc;n cel chirurgical. Concluzii. Administrarea tratamentului &icirc;n UC a determinat stoparea procesului inflamator şi dispariția sindromului dolor şi a sindromului cornean, creşterea acuității vizuale. Perioada post-chirurgicală s-a continuat cu epitelizarea completă a corneei cu formarea opacității transparente şi a opacității corneene sub formă de nubeculă.</p></description>
<description xml:lang='en' descriptionType='Abstract'><p>Introduction. According to the World Health Organization (WHO), corneal blindness is the third. The weight of corneal ulcers is from 6 to 23.2%. Objective of the study. To study etiopathogenesis and treatment effectiveness of conservative and surgical corneal ulcers and analyzing the results. Material and methods. It was a retrospective study of 31 patients, the average age was 53.87. 17 (54.83%) patients received conservative treatment. It included systemic or local administration of antibacterial agents, anti-inflammatory, detoxifying, regenerators and also cryoapplication and introducing curative lenses. 14 patients (45.17%) underwent the surgical treatment of which: 42.85% underwant cover of corneal ulcer with autoconjunctival graft, 14.29% ‒ covering corneal ulcer with free lip mucosa graft, 28.57% ‒ tectonic and curative keratoplasty; 14.29% ‒ blefarroraphy. Results. Ulcers were located in the middle or paracentral in 61.29% of cases and paralimbal in 38.61% of cases. Infiltrated areas size were 4.3&plusmn;2.2 mm. Evolution after conservative and surgical treatment was: epithelization of cornea (days) for conservative treatment was 11.6&plusmn;0.16 and 5.7&plusmn;0.11 was for surgical treatment, infiltration resorption was 8.7&plusmn;0.14 and 8.7&plusmn;0.12, resorption of hypopion was 5.8&plusmn;0.16 and 6.1&plusmn;0.15, disappearance of inflammation was 14.7&plusmn;0.14 and 12.1&plusmn;0.14, disappearance of corneal syndrome was 12.2&plusmn;0.9 and 6.1&plusmn;0.1, disappearance of pain syndrome was 12.8&plusmn;1.1 and 5.1&plusmn;0.12. Initial visual acuity of patients treated conservatively average was 0.05&plusmn;0.01 and 0.03&plusmn;0.02 for the surgical treatment. At the end of treatment, patients achieved visual acuity average 0.2&plusmn;0.01 for conservative treatment and 0.3&plusmn;0.12 for the surgical one. Conclusions. The treatment of corneal ulcers caused halting the inflammatory process and disappearance of dolor syndrome and corneal syndrome, increased visual acuity. The post-surgical period continued with complete of the cornea, transparent opacity formation and corneal opacity in the form of nubecula.</p></description>
</descriptions>
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