Aim: to asses the correlation between BMI (body mass index) and ACPA (anti-citrunillinated protein antibodies) subtypes of RA (rheumatoid arthritis), aiming to show that adipose tissue represents a risk factor in RA. Material and method: A prospective, analitical study was performed in University Clinic of Rheumatology Tg. Mures (01.03.2008-04.04.2008 – on going). The target population was represented by the patients diagnosed with RA according with ACR criteria. A number of 44 patients met the inclusion criterias. A correlation between the BMI (body mass index) and acute phase reactants was established: ESR (erythrocyte sedimentation rate, CRP (Creactive protein), anti CCP antibodies and DAS28 (Disease Activity Score). Statistically the data were analysed using the Pearson Correlation. The statistical software used was GraphPadPrism5. Results: We were unabled statistically to established a link between the BMI and anti CCP antibodies p=0.6000 (r=0.006605, Pearson r=-0.08127, 95%IC=-0.3693 to 0.2210). a similar outcome was achieved between the BMI and DAS28 (p=0.8138, r=0.001336, Pearson r=-0.03655, 95%IC=0.3299 to 0.2633). We found instead a statistically correlation between ESR and DAS28 p=0.0835 (p≤0.05). Conclusions: We couldn’t find a positive, strong association between the BMI and the outcome of RA.