P systems are a model of hierarchically compartmentalized multiset rewriting. We introduce a novel kind of P systems in which rules are dynamically constructed in each step by non-deterministic pairing of left-hand and right-hand sides. We de ne three variants of right-hand side randomization and compare each of them with the power of conventional P systems. It turns out that all three variants enable non-cooperative P systems to generate exponential (and thus non-semi-linear) number languages. We also give a binary normal form for one of the variants of P systems with randomized rule right-hand sides. Finally, we also discuss extensions of the three variants to tissue P systems, i.e., P systems on an arbitrary graph structure.