The paper describes some original experimental results obtained by applying the method of synthesis of zinc oxide structures in plasma.Crystal structures of ZnO in the shape of hollow microspheres with sizes 50-200 mm with transparent walls are presented for the first time.The device construction and technology through which the synthesis was performed were described. Photoluminescence spectra study results, surface morphology and crystalline structure of the obtained microspheres are presented. Zinc oxide is a promising semiconductor with wide band gap (Eg = 3,37 eV) and high exiton binding energy (60 meV) for applications in developing devices with ultraviolet emission and gas sensors. Among the multitude of works dedicated to ZnO structures synthesis technologies the communications on obtaining sphere-shaped micro- and nanostructures present a great interest. Unlike our results, in the works of other authors ZnO spheres have polycrystalline structure and consist in turn of nanostructures in the shape of nanorods, nanosticks or nanoneedles [1, 2 ]. The goal of this investigation was the synthesis of zinc oxide structures in the conditions of plasma obtained by impulse high tension electrical discharge and study of the obtained structures properties. The basic elements of the technological experimental installation are one electronic block which provides high voltage pulse generation and introduction of high energy in the synthesis area and chamber in which the synthesis itselt of ZnO structures takes place. In plasma obtained by impulse electric discharge the temperature values are much lower (about 2000-30000C) unlike the discharge with voltaic arc (about 60000C) and are determined by the energy parameters of the discharge impulse. Thus, regulating the tension and current values and impulse duration, different energy regimes of the synthesis of ZnO structures can be created. The experimental results have shown the possibility of synthesis of ZnO hollow microspheres with crystalline walls on silicon and mica supports with sizes between 50 and 200 mm. Changes in size and density of the obtained spheres were achieved by changing the interstice value between the Zn electrodes, discharge voltage, pulse duration and repetition frequency. The oxygen jet speed driven through the discharge area to the support and the pressure inside the chamber were determined as complementary factors. Fig.1 presents the image of hollow ZnO microspheres obtained in modulated plasma on silicon support in oxygen jet. This growth mechanism is discussed and further investigated for other metal oxide microstructures. The performed analysis by X-ray diffraction at Oxford Excalibur diffractometer allowed the identification in the microspheres walls structure of 3-5 crystalline discrete formations. The specific features of the obtained structures were analyzed by morphological characterization of the surface with electronic microscopy and by photoluminescence spectra analysis. Photoluminescence spectra of synthesized ZnO microspheres measured at 300 0K show a peak at ~390 nm (previously registered in other micro-and nanostructures of zinc oxide) and a new band centered at ~580 nm. Fabricated ZnO structures can be studied for various applications in optoelectronics and sensors.FigureFig.1 ZnO hollow microspheres obtained in