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Articolul urmator |
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Ultima descărcare din IBN: 2023-09-15 11:23 |
SM ISO690:2012 PROCA, Ion, BAJURA, Cătălina, ROITBURT, Alexander, GRĂJDIERU, Romeo. Predictorii mortalității în endocardita infecțioasă. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 252. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 252-252 | ||||||
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Rezumat | ||||||
Background. Infective Endocarditis (IE) is an endovascular microbial infection with high mortality. The incidence of IE varies between 3-10 episodes per 100.000 people annually, the male/female ratio is 2:1. In-hospital mortality is 15-20%. Objective of the study. To determine the predictors of mortality in infective endocarditis. Material and Methods. A retrospective-prospective study, included 161 patients with clinical and paraclinical evidence of IE, admitted between 2013-2019 at the Institute of Cardiology and Municipal Clinical HospitalThe Holy Trinity”. Patients were divided into two groups: survived 130 (80,7%) and deceased 31 (19,3%). Men represented 73,9% (n=119) and women 26,1% (n=42), m/f ratio 2,8:1, average age 52,5±13 years. Results. Predictors of mortality in patients with IE in our study were: diabetes mellitus (OR 4,0; CI 95%, 1,51-10,7; p<0,05), positive blood culture (OR 3,4; CI 95%, 1,51-7,67; p<0,05), pathogens Staphylococcus aureus (OR 4,4; CI 95%, 1,47-13,42; p<0,05), Staphylococcus epidermidis (OR 4,7; CI 95%, 1,09-19,83; p<0,05), vegetation on three valves (OR 7,8; 95% CI, 1,23-50,4; p<0,05), embolies (OR 9,3; 95% CI, 3,87-22,1; p<0,001), heart failure NYHA IV (OR 2,9; 95% CI, 1,08-7,66; p<0,05), septic shock (OR 8,5; 95% CI, 2,74-26,1; p<0,001), acute renal failure (OR 4,7; CI 95%, 1,09-9,83; p<0,05) and heart abscess (OR 13,8; 95% CI, 1,4-137,8; p<0,05). Conclusion. There are risk factors in our study that serve as predictors of mortlity in patients with infective endocarditis. These predictors can identify those patients eligible for an unhesitating and suitable antibiotic therapy, and/or urgent surgical intervention. |
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Cuvinte-cheie Infective endocarditis, predictors of mortality, endocardita infecțioasă, predictorii mortalității |
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