In drinking water, heavy metals can reach through domestic installations, and their presence in high concentrations can seriously damage human health. The heavy metals are naturally present in soil and water, some are considered indispensable for life, but, in high concentrations, those may become toxic; copper, zinc, manganese, iron, etc. are just a few examples. However, in low concentrations, some elements like cadmium, mercury, lead, nickel, and chromium are considered also toxic and are included in another category of heavy metals. In present, the existing information about the occurrence of heavy metals in the water designed to be used by the urban population from Targoviste city, Romania is insufficient. In this respect, the present inquiry aims to provide a water-quality data set by using consistent sampling methods and analysis, correlated with health index risk data and potential influence on human health. In this study 360 samples from capture groundwater stations, which deserved the Targoviste city area were collected. The measurements of water temperatures, pH, electrical conductivity, total dissolved solids, and salinity were performed using multiparameter equipment (Consort 3030). Alkalinity was determined by titration methods in order to quantify the carbonate species in the drinking water samples. The metals (Cd, Cr, Ni, Pb, Cu, Mn, and Zn) were measured in the drinking water samples using inductively coupled plasma-mass spectrometry (iCAP™ Q ICP-MS). The average concentrations of heavy metals were correlated with physicochemical indicators. The results indicate that for only one groundwater station the metals may pose a detrimental health risk to the exposed population.