Introduction. Radical cystectomy and radical prostatectomy are challenging and demanding procedures with a great impact on the patients. In order to reduce the repercussions on quality of life, and to facilitate the social reintegration, for these complex surgeries the laparoscopic approach could be the solution. Aim of the study. To evaluate the feasibility of 3D laparoscopy as an approach for the surgical treatment of pelvic urologic malignancies: prostate cancer (intermediate and high risk patients) and muscle invasive bladder cancer Materials and methods. Between June 2017 and March 2018 we performed 16 laparoscopic 3D radical prostatectomies for intermediate and high risk prostate cancer (11 extraperitoneal and 5 transperitoneal). The median (range) patient age was 66 years; body mass index 32 kg/m2 ; PSA level >10 ng/mL and biopsy Gleason ≥7. All patients had a pelvic lymphadenectomy, which was performed using an extended template. A partial nerve-sparing technique was used in all the patients. In the same period, 4 men and 2 women with bladder cancer underwent laparoscopic radical cystectomy with direct cutaneous ureterostomy. For performing this procedure we used a 5-port technique, a 3D laparoscopic video system and for haemostasis 5mm bipolar vessel sealing device and polymer clips (5 and 10mm) for larger vessels. Results. Laparoscopic radical prostatectomy: the mean operating time 155 (110-270 min) blood loss 340 (100-950) mL; postoperative hospitalization 6. (4-9) nights; catheterization time 21 days; lymph node (LN) count 12. According to the pathology report most of the cases were pT2c 50%, pT3b 33% and pT3a 17% and a prostate cancer Gleason 7: 54%, Gleason 9:33%, Gleason 8:13% pT3b. Positive surgical margin (PSM) rate 25%. In the extraperitoneal group the hospitalization was shorter due to earlier bowel recovery and drain removal. Laparoscopic radical cystectomy: The mean time to perform the laparoscopic radical cystectomy, including the lymph node dissection, was 265 minutes (range 240–300). Mean estimated blood loss was 300 ml (range 100–600ml). Mean hospital stay was 7 days (range 5–9). In female patients the specimen was extracted by vaginal route using an endobag. All cases were pT3bN0Mx with negative surgical margins and a mean number of 14 lymph nodes. In 2 cases a synchronous prostate cancer was diagnosed after the pathology report (PSA<4ng/ml). No cases required conversion to open surgery and no major complication are noted during or after surgery. Conclusions. 3D laparoscopy in feasible for surgical treatment of pelvic urologic malignancies.