Introduction. Gastrointestinal bleeding is by far the most severe and life-threatening complication of portal hypertension in cirrhotic patients. The location of the varices is tightly bound to the management of the patient, especially as regards to the endoscopic haemostasis; hence the gastric varices have a more difficult approach than the esophageal one. Consequently the gastric variceal bleeding might have a more reserved prognosis. Aim of the study. The comparison of evolution and prognosis of patients after an episode of upper gastrointestinal bleeding through a variceal outburst according to the site of bleeding (gastric varices versus esophageal varices). Materials and methods. We conducted a retrospective study which included 214 patients and comprised 310 variceal bleeding episodes through the year 2017 (patients who were admitted to the emergency room of Bucharest Clinical Emergency Hospital “Floreasca”). For 61/310 (19.7%) observations the etiology was represented by gastric varices. Results. Regarding the management of patients, the therapeutic mean chosen in majority of cases was the endoscopic haemostasis through ligation (89% out of 310 episodes); whilst for a smaller percentage – cyanoacrylate injections and Sengstaken-Blakemore tube were chosen. Amongst the patients with gastric varices we recorded a higher mortality in comparison with patients with oesophageal variceal bleeding (15.8% vs. 8%). Likewise, there was a difference suggesting a slightly higher severity of gastric varices bleeding considering the mean value of hemoglobin at admission (7.3 g% vs. 8.31 g%) and duration of hospitalization (4.8 vs. 3.8 days). Conclusion. Despite similar modalities of management for the two types of variceal outburst, gastrointestinal bleeding from gastric varices is strained by a lugubrious prognosis and evolution. Therefore these patients should undergo a more thorough and specific management and follow-up.