Towards Mimics of Forskolin. Efficient Free Radical Alkylations of Manoyloxides

Morărescu (Chetraru) Olga; Gîrbu Vladilena; Pruteanu Elena; Ungur Nikon; Kulciţki Veaceslav; Renaud Philippe

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2023-08-15 15:27

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MORĂRESCU (CHETRARU), Olga, GÎRBU, Vladilena, PRUTEANU, Elena, UNGUR, Nikon, KULCIŢKI, Veaceslav, RENAUD, Philippe. Towards Mimics of Forskolin. Efficient Free Radical Alkylations of Manoyloxides. In: Medical Plants – present and perspectives: Dedicated to the 60-year celebration of the „Stejarul” Biological Research Centre, 6-9 septembrie 2016, Piatra Neamț. Piatra Neamț, România: NIRDBS/„Stejarul“ Biological Research Centre, 2016, Ediția a 12-a, pp. 126-127. ISSN Print ISSN: 1223-6578 Online ISSN: 2247-2711.

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Medical Plants – present and perspectives
Ediția a 12-a, 2016

Simpozionul "Medical Plants – present and perspectives"
Piatra Neamț, Romania, 6-9 septembrie 2016

Towards Mimics of Forskolin. Efficient Free Radical Alkylations of Manoyloxides

Pag. 126-127

Morărescu (Chetraru) Olga¹², Gîrbu Vladilena¹², Pruteanu Elena¹², Ungur Nikon¹², Kulciţki Veaceslav¹², Renaud Philippe³

¹ Institute of Chemistry of the Academy of Sciences of Moldova,
² University of the Academy of Sciences of Moldova,
³ University of Bern

Disponibil în IBN: 6 august 2020

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Rezumat

The current work presents the first results on the application of the radical addition
methodology for the simultaneous attachment of a C-2 synthon and a functional group to the
manoyloxide framework, wich resembles the well known bioactive natural product forskolin.

Cuvinte-cheie
Carboiodination, Carboazidation, radical chemistry, diterpene, labdane