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SM ISO690:2012 ZANOAGA, Madalina, TANASA, Fulga. Antimicrobial reagents as functional finishing for textiles intended for biomedical applications. I. Synthetic organic compounds. In: The International Conference dedicated to the 55th anniversary from the foundation of the Institute of Chemistry of the Academy of Sciences of Moldova, 28-30 mai 2014, Chișinău. Chișinău, Republica Moldova: Institutul de Chimie al AȘM, 2014, p. 220. |
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The International Conference dedicated to the 55th anniversary from the foundation of the Institute of Chemistry of the Academy of Sciences of Moldova 2014 | ||||||
Conferința "The International Conference dedicated to the 55th anniversary from the foundation of the Institute of Chemistry of the Academy of Sciences of Moldova" Chișinău, Moldova, 28-30 mai 2014 | ||||||
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Common problem in hospitals and healthcare institutions is microbial contamination of |
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Cerif XML Export
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Synthetic organic compounds</cfTitle> <cfAbstr cfLangCode='EN' cfTrans='o'><p>Common problem in hospitals and healthcare institutions is microbial contamination of<br />surfaces, including textile fabrics, which can lead to infections and, consequently, to crossinfections.<br />Irrespective of their applications, internal (surgical threads and various implants) or<br />external (various extracorporeal devices such as catheters and hollow fibers for dialyzers,<br />gauzes, bandages, nappies, tampons), medical textiles have to be comprised of basic bioactive<br />properties, especially antimicrobial. Also, it is extremely important for protective clothing<br />(surgical masks, caps, gowns, etc.) and hospital linen to meet the demands for antimicrobial<br />protection.<br />As a consequence, the number of different technological approaches, antimicrobial agents<br />and methods of binding them to the substrate, suitable for textiles, has increased significantly.<br />The development of new antimicrobials with enhanced activity is an ongoing topic of research<br />and targets products ranging from synthetic to naturally based biocides: quaternary ammonium<br />compounds, dyes and regenerable N-halamines, polyhexamethylene biguanides, peroxyacids,<br />metals and metal oxides (silver, copper, titanium, cobalt, etc.), chitosan, essential oils, enzymes,<br />natural pigments, etc.<br />This article offers an overview of some contemporary antimicrobial agents used as<br />functional finishing for textiles intended for biomedical applications. It reviews only the<br />synthetic organic compounds, namely quaternary ammonium compounds, halogenated phenols,<br />polybiguanides, N-halamines, and renewable peroxides, as part of an extensive study. Taking<br />into consideration various criteria, antimicrobial activity, toxicity, durability and ecological<br />acceptability, these agents can be divided into several groups, as follows: biocides and biostats,<br />leaching and bound antimicrobials, controlled-release and barrier-forming agents, and agents<br />with poor and good washing resistance [1]. Since the societal demand for medical textiles with<br />biocide activity is growing, as well as their disposal, the importance of the environmental point<br />of view increased. Therefore, the research has focused on the design and synthesis of new<br />antimicrobials able to covalently bond to the fibers surface, in order to replace the leaching ones.<br />Thus, textiles finishing stability increased with beneficial impact on their medical applications.<br />Examples of commercial antimicrobial products are presented herein, as well as the<br />corresponding finishing methods.<br />References:<br />1. Khanna, G. Antimicrobial finishes for textiles. Melliand International, 2006, 2, pp. 146-151.</p></cfAbstr> <cfResPubl_Class> <cfClassId>eda2d9e9-34c5-11e1-b86c-0800200c9a66</cfClassId> <cfClassSchemeId>759af938-34ae-11e1-b86c-0800200c9a66</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> </cfResPubl_Class> <cfResPubl_Class> <cfClassId>e601872f-4b7e-4d88-929f-7df027b226c9</cfClassId> <cfClassSchemeId>40e90e2f-446d-460a-98e5-5dce57550c48</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> </cfResPubl_Class> <cfPers_ResPubl> <cfPersId>ibn-person-44313</cfPersId> <cfClassId>49815870-1cfe-11e1-8bc2-0800200c9a66</cfClassId> <cfClassSchemeId>b7135ad0-1d00-11e1-8bc2-0800200c9a66</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> </cfPers_ResPubl> <cfPers_ResPubl> <cfPersId>ibn-person-44314</cfPersId> <cfClassId>49815870-1cfe-11e1-8bc2-0800200c9a66</cfClassId> <cfClassSchemeId>b7135ad0-1d00-11e1-8bc2-0800200c9a66</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> </cfPers_ResPubl> </cfResPubl> <cfPers> <cfPersId>ibn-Pers-44313</cfPersId> <cfPersName_Pers> <cfPersNameId>ibn-PersName-44313-3</cfPersNameId> <cfClassId>55f90543-d631-42eb-8d47-d8d9266cbb26</cfClassId> <cfClassSchemeId>7375609d-cfa6-45ce-a803-75de69abe21f</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> <cfFamilyNames>Zanoaga</cfFamilyNames> <cfFirstNames>Madalina</cfFirstNames> </cfPersName_Pers> </cfPers> <cfPers> <cfPersId>ibn-Pers-44314</cfPersId> <cfPersName_Pers> <cfPersNameId>ibn-PersName-44314-3</cfPersNameId> <cfClassId>55f90543-d631-42eb-8d47-d8d9266cbb26</cfClassId> <cfClassSchemeId>7375609d-cfa6-45ce-a803-75de69abe21f</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> <cfFamilyNames>Tanasa</cfFamilyNames> <cfFirstNames>Fulga</cfFirstNames> </cfPersName_Pers> </cfPers> </CERIF>