Articolul precedent |
Articolul urmator |
641 0 |
SM ISO690:2012 LUPASCU, Tudor, TIMBALIUC, Nina, GONTA, Alexandru. Monitoring of the dynamics of functional acidic groups in the pharmaceutical preparation of enoxil. In: The International Conference dedicated to the 55th anniversary from the foundation of the Institute of Chemistry of the Academy of Sciences of Moldova, 28-30 mai 2014, Chișinău. Chișinău, Republica Moldova: Institutul de Chimie al AȘM, 2014, p. 164. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
The International Conference dedicated to the 55th anniversary from the foundation of the Institute of Chemistry of the Academy of Sciences of Moldova 2014 | ||||||
Conferința "The International Conference dedicated to the 55th anniversary from the foundation of the Institute of Chemistry of the Academy of Sciences of Moldova" Chișinău, Moldova, 28-30 mai 2014 | ||||||
|
||||||
Pag. 164-164 | ||||||
|
||||||
Descarcă PDF | ||||||
Rezumat | ||||||
One of the negative consequences of social development is the massive pollution of the The investigation results allow us to conclude that the total content of acidic functional groups,
|
||||||
|
Cerif XML Export
<?xml version='1.0' encoding='utf-8'?> <CERIF xmlns='urn:xmlns:org:eurocris:cerif-1.5-1' xsi:schemaLocation='urn:xmlns:org:eurocris:cerif-1.5-1 http://www.eurocris.org/Uploads/Web%20pages/CERIF-1.5/CERIF_1.5_1.xsd' xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' release='1.5' date='2012-10-07' sourceDatabase='Output Profile'> <cfResPubl> <cfResPublId>ibn-ResPubl-106282</cfResPublId> <cfResPublDate>2014</cfResPublDate> <cfStartPage>164</cfStartPage> <cfISBN></cfISBN> <cfURI>https://ibn.idsi.md/ro/vizualizare_articol/106282</cfURI> <cfTitle cfLangCode='EN' cfTrans='o'>Monitoring of the dynamics of functional acidic groups in the pharmaceutical preparation of enoxil</cfTitle> <cfAbstr cfLangCode='EN' cfTrans='o'><p>One of the negative consequences of social development is the massive pollution of the<br />environment with chemical, biological, physical and other agents, which adversely affect human<br />health, in particular, through the formation of free radicals. Contemporary medicine recommends<br />in such cases the use of biologically active substances obtained from natural raw materials,<br />which exhibit remarkable antioxidant properties [1]. Grape seeds are a valuable source for<br />obtaining enotannins, natural compounds of polyphenol structure, which possess particularly<br />important antioxidant properties. In this work Enoxil, a polyphenol compound with antioxidant,<br />antibacterial and antifungal properties, have been used.[1] One of the basic principles of the<br />prolonged activity of a pharmaceutical product is its stability in time, according to the lifespan<br />on the label. In order to determine the stabilty of the Enoxil product, it have been investigated the<br />total content of the acidic functional groups (carboxyl and phenolic, TCP). Therefore, the acidbase<br />titration method has been chosen for the analysis of TCP parameter, according to Boehm’s<br />method with slightly modifications. Monitoring of this parameter was performed over five years,<br />obtained results are shown in the table 1.<br />Table 1. Total content of functional acidic groups (carboxyl and phenolic) determined in 5%<br />aqueous solutions (calculated per 1.0 g of solution 5% Enoxil)</p><p>The investigation results allow us to conclude that the total content of acidic functional groups,<br />determined in 5% aqueous Enoxil solution, are practically the same throughout the product<br />storage time, which means that Enoxil is stable for at least 5 years.<br />Acknowledgment. The research leading to these results has received funding from the People<br />Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme<br />FP7/2007-2013/ under REA grant agreement n° PIRSES-GA-2013-612484<br />References:<br />[1] Lupaşcu, T.; Duca, Gh.; Gonciar, V. Enoxil preparat ecologic pentru sănătatea omului″,<br />Monografie, Editura ″Ştiinţa″, Chişinău, 2012, 256 p.</p><p> </p></cfAbstr> <cfResPubl_Class> <cfClassId>eda2d9e9-34c5-11e1-b86c-0800200c9a66</cfClassId> <cfClassSchemeId>759af938-34ae-11e1-b86c-0800200c9a66</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> </cfResPubl_Class> <cfResPubl_Class> <cfClassId>e601872f-4b7e-4d88-929f-7df027b226c9</cfClassId> <cfClassSchemeId>40e90e2f-446d-460a-98e5-5dce57550c48</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> </cfResPubl_Class> <cfPers_ResPubl> <cfPersId>ibn-person-679</cfPersId> <cfClassId>49815870-1cfe-11e1-8bc2-0800200c9a66</cfClassId> <cfClassSchemeId>b7135ad0-1d00-11e1-8bc2-0800200c9a66</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> </cfPers_ResPubl> <cfPers_ResPubl> <cfPersId>ibn-person-12499</cfPersId> <cfClassId>49815870-1cfe-11e1-8bc2-0800200c9a66</cfClassId> <cfClassSchemeId>b7135ad0-1d00-11e1-8bc2-0800200c9a66</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> </cfPers_ResPubl> <cfPers_ResPubl> <cfPersId>ibn-person-27170</cfPersId> <cfClassId>49815870-1cfe-11e1-8bc2-0800200c9a66</cfClassId> <cfClassSchemeId>b7135ad0-1d00-11e1-8bc2-0800200c9a66</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> </cfPers_ResPubl> </cfResPubl> <cfPers> <cfPersId>ibn-Pers-679</cfPersId> <cfPersName_Pers> <cfPersNameId>ibn-PersName-679-3</cfPersNameId> <cfClassId>55f90543-d631-42eb-8d47-d8d9266cbb26</cfClassId> <cfClassSchemeId>7375609d-cfa6-45ce-a803-75de69abe21f</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> <cfFamilyNames>Lupascu</cfFamilyNames> <cfFirstNames>Tudor</cfFirstNames> </cfPersName_Pers> </cfPers> <cfPers> <cfPersId>ibn-Pers-12499</cfPersId> <cfPersName_Pers> <cfPersNameId>ibn-PersName-12499-3</cfPersNameId> <cfClassId>55f90543-d631-42eb-8d47-d8d9266cbb26</cfClassId> <cfClassSchemeId>7375609d-cfa6-45ce-a803-75de69abe21f</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> <cfFamilyNames>Timbaliuc</cfFamilyNames> <cfFirstNames>Nina</cfFirstNames> <cfFamilyNames>Цымбалюк</cfFamilyNames> <cfFirstNames>Нина</cfFirstNames> </cfPersName_Pers> </cfPers> <cfPers> <cfPersId>ibn-Pers-27170</cfPersId> <cfPersName_Pers> <cfPersNameId>ibn-PersName-27170-3</cfPersNameId> <cfClassId>55f90543-d631-42eb-8d47-d8d9266cbb26</cfClassId> <cfClassSchemeId>7375609d-cfa6-45ce-a803-75de69abe21f</cfClassSchemeId> <cfStartDate>2014T24:00:00</cfStartDate> <cfFamilyNames>Gonta</cfFamilyNames> <cfFirstNames>Alexandru</cfFirstNames> </cfPersName_Pers> </cfPers> </CERIF>