 Modern physical vector of the development of inorganic chemistry (including coordination chemistry) of compounds, substances, materials.  Definitions of physico-inorganic coordination chemistry.  Activation energies of particles: thermal, chemical, photochemical, electrochemical, ultrasonic activation energy, activation energy of collision with fast electrons, etc.  Transformation of physical methods, which are becoming not only research methods, but also synthetic methods: chromatography, mass-spectrometry, electron microscopy, laser physicochemistry, etc.  Modern syntheses of substances using physical methods of action: – high-temperature and cryochemical syntheses; – plasma syntheses; – high-pressure syntheses, including shock-wave synthesis; – mechanical, tribochemical syntheses, including ultrasonic and microwave syntheses; – electrosyntheses; – syntheses using light, radiation, laser action; – syntheses using charged particles: arc, glow discharge, magnetron sputtering, etc; – atom manipulation: atomic-force microscopy, light “forceps”, motion in electric fields, etc.  Examples of goal-directed physico-inorganic synthesis and use of functional substances and materials based on coordination compounds: – tribodiffusion modification of metal surfaces by molybdenyl hydroxamate complexes; – stabilization of semiconducting metal chalcogenide nanoparticles with nanoreactors of supramolecular liquid-crystal systems – metal alkanoate complexes; – photoelectrochemistry of composites based on phthalocyanine complexes of Cu, Ni, In, Sb, Zr, Hf grafted on Ti, W, Zr oxide films; – catalytically active rhodium selenohalide complexes for the oxidative carbonylation of methane into methanol, ethanol, acetic acid, etc; – thermal synthesis of nanoscale hybrid Al2O3–C–PdLn catalysts (where Ln = (dba)2) for carrying out Heck, Suzuki, Sonogashira cross-coupling reactions with a yield of up to 98%; – high-frequency low-temperature plasmochemical (PE MOCVD) synthesis of germanium nanostructures using highly volatile germanium -diketonate complexes.