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SM ISO690:2012 BÎSTRIŢCHI, Ina, HOLBAN, Tiberiu, IAROVOI, Liviu, NAGÎŢ, Angela. Tratamentul antiretroviral cu regimuri terapeutice de I linie al pacienţilor cu HIV/SIDA. In: Sănătate Publică, Economie şi Management în Medicină , 2012, nr. 5(44), pp. 164-167. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | ||||||
Numărul 5(44) / 2012 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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Pag. 164-167 | ||||||
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Clinical, immunological, virological and epidemiological data were collected in 40 adult patients diagnosed with HIV/AIDS infection. Late diagnoses were defi ned as a CD4 count of < 350 cells/μl and/or an AIDS associated condition. More than half (70%) of the investigated patients had at the time of diagnosis severe immunosupression and/ or clinical AIDS. The most frequent AIDS related conditions were tuberculosis, oropharyngeal candidiasis and wasting syndrome. Effectiveness of ART regimen applied appreciated in terms of virological response is higher for I regimen (3TC+EFV+AZT), and in terms of immunologic response is higher for II regimen (TDF+FTC+EFV). The dissociated virological and immunological response at HAART, registered for some of the patients, in many cases is the result of insuffi cient adherence to treatment, which increases the risk of progression of the disease. |
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Cuvinte-cheie HIV/AIDS infection, antiretroviral therapy, late diagnoses, ВИЧ/СПИД инфекция, противовирусная терапия, поздняя диагностика |
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