Semnificaţia testelor de biologie moleculară &icirc;n detectarea unor markeri ai rezistenţei E. coli la antibiotice

Burduniuc (Popa) Olga; Cojocaru Radu; Roşcin Iurie; Spânu Constantin

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2023-01-08 19:26

SM ISO690:2012

BURDUNIUC (POPA), Olga, COJOCARU, Radu, ROŞCIN, Iurie, SPÂNU, Constantin. Semnificaţia testelor de biologie moleculară în detectarea unor markeri ai rezistenţei E. coli la antibiotice. In: Sănătate Publică, Economie şi Management în Medicină , 2012, nr. 5(44), pp. 154-157. ISSN 1729-8687.

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Sănătate Publică, Economie şi Management în Medicină

Numărul 5(44) / 2012 / ISSN 1729-8687 /ISSNe 2587-3873

Semnificaţia testelor de biologie moleculară în detectarea unor markeri ai rezistenţei E. coli la antibiotice

Signifi cance tests for detection of molecular biology E. Coli markers the antibiotic resistance

Значение биолого-молекулярных тестов для определения маркеров резистентности кишечной палочки к антибиотикам

Pag. 154-157

Burduniuc (Popa) Olga¹, Cojocaru Radu¹, Roşcin Iurie², Spânu Constantin¹

¹ Centrul Naţional de Sanătate Publică,
² Institutul de Microbiologie şi Biotehnologie al AŞM

Disponibil în IBN: 18 mai 2020

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In the current context of rapid increase in the prevalence of resistant strains of Enterobacteriaceae, the need to use methods of molecular biology is becoming increasingly stringent, which is far more sensitive than phenotypic testing and surveillance and epidemiological monitoring of strains producing CTX-M are important in determining treatment tactics for review empirical treatment protocols. Our study is something new for our country by molecular analysis of plasmid genes with great potential for the communities.

В нынешних условиях быстрого роста и распространенности резистентных штаммов Enterobacteriaceae, необходимо использовать методы молекулярной биологии, являющиеся гораздо более чувствительными, чем фенотипическое тестирование. Эпидемиологический мониторинг штаммов, продуцирующих CTX-М, является важным для определения тактики лечения и рассмотрения эмпирических протоколов лечения. Проводимые нами исследования, молекулярный анализ плазмидных генов с большим потенциалом распространения в лечебнодиагностических учреждениях, являются новыми для нашей республики.

Cuvinte-cheie
antibiotic resistance, monitoring, phenotype, molecular biology, extended spectrum beta-lactamases, CTX-M,

устойчивость к антибиотикам, мониторинг, Фенотип, молекулярнaя биология, бета-лактамазы расширенного спектра, CTX-М

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