The innovative series of MRI CryoCoils deliver ultra-high spatial resolution in vivo, showing brain structures of single cortical layers bringing you closer to the molecular level research. They feature very low temperature closed cycle cooled RF-coils and preamplifiers offering an increase in signal-to-noise ratio (SNR) by a factor of 2 or more over standard room temperature RF-coils in routine MRI applications. Animal handling and supervision of the MRI CryoiProbes is very similar to standard room temperature RF-coils. CryoProbe cooling can be accomplished outside the magnet ensuring optimum usage of the scanner time. Extending NMR cryogenically-cooled probe technology to MRI microscopy leads to new and exciting opportunities in the micro-imaging field. Microimaging techniques for small sample sizes up to 5mm benefit from new MRI CryoProbe products in form of improved image quality, increased spatial resolution and/or reduced scan times due to the improvements in signal-to-noise up to a factor of 4. The probes feature a temperature range from 0 to 80°C and are used with a Bruker BioSpin Micro 2.5 gradient system in vertical magnets between 400 and 600MHz with bore sizes of 89mm and above. Next to 1H micro-imaging CryoProbes now also a dual 1H/ 13C CryoProbe is available. The key applications are investigations on plants, insects and other small animals, embryos and histological tissue samples. Porous and inhomogeneous objects can be studied with highest sensitivity at intermediate field strengths, allowing to maintain a minimum of susceptibility distortions.