This paper presents the results of the research on the impact of the difficult life situation, in the given case of the changes in the educational system imposed by the Covid-19 pandemic, on the well-being and anxiety of adolescent, arguing the need to manage anxiety by increasing the well-being. The results of the research confirmed the hypothesis: well-being and its manifestations appear as factors that diminish and even eliminate the manifestations of anxiety as a trait and as a state, but also of school anxiety among adolescents. Through correlation calculations it was established: 1) the feeling of happiness excludes social stress (p<0.01), fear of self-expression (p<0.05), fear of school testing (p<0.03), of not coping with social expectations (p=0.01), in general, school anxiety (p<0.03); 2) self-acceptance correlates negatively with social stress (p<0.01), frustration of social needs (p<0.01), fear of not meeting social expectations (p<0.03), in general, with school anxiety (p<0.01); 3) the ability to monitor the environment is indirectly related to social stress (p<0.01), frustration of social needs (p<0.01), fear of not meeting social expectations (p<0.05), in general, with school anxiety (p<0.01); 4) the spirit of autonomy indirectly correlates with the fear of self-expression (p<0.03) and communication with teachers (p<0.03); 5) well-being is favorable for removing social stress (p<0.01), frustration of social needs (p<0.01), fear of self-expression (p<0.03), communication with teachers (p<0 .03), in general, of school anxiety (p<0.01).