This article addresses the problems related to the significance of the concept of the cultural space of contemporary society arising from the context of the dialectical connection between culture and civilization. The author refers to the definitions of the categories of „culture” and „civilization”, „cultural space”, and then refers to the concept of cultural space of the 21st century society, which isin process continuous of globalization. In conclusion, it is remarked that a definite imperative of the romanian existence is the need to reshape the concept ofthe culturalspace, especially in the Republic of Moldova,to reorientittowardsthe European values of an „open society”, focused on new moral criteria.