The article shows the ways of ensuring national interests and economic security of the state at the present stage. Economic security is an important object of economic diplomacy of States. In the Human Development Report 2005 of the United Nations Development Program, security is presented as the third pillar of cooperation in a globalized world, and the concept of security, not limited to military problems, is formulated in a new way. The contemporary nature and geography of conflicts have changed. Economic security is not only the protection of national interests, but also the willingness and ability of state institutions to create mechanisms for the implementation and protection of national interests in the development of the domestic economy, maintaining social and political stability of society. In the era of globalization, economic diplomacy is an important component of the foreign policy of any state, it has become one of the key elements of modern international relations. Acting as the main mechanism for building profitable trade and economic relations on a bilateral and multilateral basis, economic diplomacy helps States, despite their differences in social structure, state structure, level of economic development, to effectively overcome contradictions and create strong partnerships