In recent years, the increasing industrialization causing the environmental pollution becoming a serious problem to human health and need to be addressed [1]. The waste water from various industries contains many toxic organic compounds with small concentration. The advanced oxidation process (heterogeneous photocatalysis) can be one of the green and clean way to reduce the toxic organic compounds to nontoxic inorganic compound with CO2 and water as product. The process involves the catalyst activated by light produces ROS (reactive oxygen species) further reacts the target molecules [2]. The organic-inorganic based composite as photocatalyst attracts tremendous attention due to its better efficiency of separation of photogenerated charge carriers than the single phase photocatalyst [3]. We report, the graphitic carbon nitride layered sheet coated with indium sulfide nanoparticles for enhanced photocatalytic activity for rhodamine B degradation under visible irradiation. Composite samples showed the increased photocatalytic activity nearly 7 times higher than gC3N4 and 16 times higher than In2S3. The photoluminescence and photocurrent measurement exhibits the higher lifetime of charge carriers in the composite system than pure gC3N4. The optical study showed the composite exhibits the increased UV-visible absorption than the gC3N4. The band gap energies calculated for gC3N4 and In2S3 and were found to be 2.8 and 2.25 eV. The absorption edge of composite spectra exhibits red shift with increase In2S3 concentration. The photocatalytic activity of In2S3/gC3N4 nanocomposite have strong dependence of pH of solution. The acidic pH of RhB dye increases activity by increasing the adsorption sites. The enhanced activity for In2S3/gC3N4 nanocomposite can be the combination of superior charge separation and increased visible light absorption [3]. The In2S3/gC3N4 nanocomposite having suitable band potential exhibits staggered type II band alignment separates the charge carriers across the interface mostly responsible for enhances activity.