Introduction Viticulture in the Republic of Belarus (RB) is now in its infancy, hereupon proper Vitis selection work still not developing. Practically all grape wine cultivars are foreign or in process of introduction, that implicate preliminary studies of varietal characteristics in planted collections & nurseries of Vitis sp. The acclimatization advances for assortment (diversifi cation) depends on degrees of alien crops ecological plasticity and their positive reactions in response to growing technologies. Scientifi c foundations for grape wine introduction with regard to different climatic zones were developed by A.M. Negrul (1938–1965) [1]. The viticulture possibility is stipulated by sum of active temperatures (SAT) and duration of vegetation period. Material and methods Council of Ministers of the Republic of Belarus from 31.12.2010 No1926 “On State Integrated Programme for Development of potato, vegetable and fruit growing in 2011–2015” (Council of Ministers release from 22.12.2012 No1193). Results and discussions Grape wine propagation in RB proceeds due to implication of climate. On the global warming background Belarus experiences the gradual widening of northern Vitis frontier and also boundaries of other heat-lovers (soya, maize, walnut, apricot) – that was the problem several decades ago. RB situated between 56º & 51º of northern latitude, including three main agroclimatic zones (AZ). According to academician V.F. Loginov [2], the borders of south- & central- AZ changed (150 km northward). Along with SAT, the frost-free period increased for 12÷18 days. The vegetation of plants reaches 120÷145 days. The insolation augments from 3500 МJ/m2 (RB north) to 4100 МJ/m2 (RB south). Belarus territory is considered as area of risk farming and pertains to 5-th climatic winter hardiness zone – WHZ 5, T from -23.3°С to -28.9°С (Heinze and Schreiber, 1984). Note should be taken − Northern viticulture gives some advantages. So, more durable winter period with low temperature in RB prevents development of quarantine grape pest phylloxera (Viteus vitifolii). In addition several hazardous grape diseases (grapevine fanleaf virus, grapevine yellow mosaic virus) are absent in Belarus. The grape fungal infections (powdery mildew, oidium, gray mold) are less aggressive due to moderate temperatures of Vitis vegetation period. Thus number of pesticide treatments are not needed or reduced to prophylaxis. Conclusions The Vitis cultivars (cvs) of Russian (Krasa severa, Cosmonaut, Cosmos, Agat donskoi), and Baltic (Zilga, Supaga) selection are already zoned (regionalized) in RB. The cvs: Bianca, Kristall, Platovskij, Augusta, Regent, also hardy cvs: (S 675, Maréchal Foch – neukryvnyh) are now on-stream in the state variety trials because they are worth-while for local viticulture –disease resistant endowed with biological plasticity. New complex-resistant varieties of grapes were created during last decades using the some Franco-American cvs crossed with V. vinifera. These interspecies hybrids are next best (compared with traditional European that one’s). The reliable hardy cvs of American selection (e.g. Adalmiina, Prairie Star etc.) correspond most valuable for Belarus, as well breeding new items: Briana, Marquette, Frontenac Gris, Somerset Seedless [3]. All of them characterized by high resistance to cold and can be grown in RB without winter shelter (at minimal needed pesticides treatment) – excellent opportunity for development in Belarus the organic (ecological-friendly) viticulture.