The progress observed in modern analytical chemistry is the consequence of civilisation development. Higher and higher expectations as for decreasing the determination level of particular analytes in complex matrices make analysts search for new methodological and instrumental solutions. Combining particular techniques into multi-dimensional and hybrid systems is the future of analytical chemistry and challenges in environment monitoring. This is possible due to outstanding achievements in chromatography and related techniques, especially:  packing and columns technology,  miniaturisation,  automation and robotics,  application of new selective detection systems,  advancement in sample preparation,  qualitative and quantitative determinations - validation. This contribution is devoted to discussing the above problems.