LDPE based wrapping, protection and other covers become waste after once used. Rapid increase of the amount of their waste is observed because of the short service period of the products used in everyday life, technical and other fields and great demand. It is possible to characterize polymer waste included into this group:  As their exploitation period is short they don't undergo to deep aging processes;  Weak structural-chemical changes take place in polymer mass because of thermo-mechanical influences of initial treatment;  Sharp change of physic-mechanical properties useful for exploitation isn’t observed;  Rheological indices are useful for treatment. The above mentioned requires special approach to the research process of content and properties of compositions materials based on corresponding group LDPE wastes. In the secondary treatment of these polymers it is possible to use indices expediently according to exploitation condition requirements. Providing of biological activity during preparing of composition materials for definite technical items touched by humans is necessary. According to the researches following advantages of the use of nanosize biological active substances are possible:  Biological activity – antimicrobe influence of nanosize substance is many times more;  It is possible for nanosize biological active substance to create more homogenous phase in polymer mass;  Being of antimicrobe substance nanosize reduces its migration from its polymer mass to minimum because of a number of influences; The 6th International Conference ECOLOGICAL & ENVIRONMENTAL CHEMISTRY-2017 www.eec-2017.mrda.md, March 2-3, 2017, Chisinau, Republic of Moldova 94  Polymer mass makes possible antimicrobe additive- nanoparticle activity to be stable;  Use of nanoparticle antimicrobe substance as a component of exploited LDPE based composition increases its service period and etc. In the research work carried out in this direction influences of crystal biological active substances have been studied comparatively. It is considered that providing of biological activity of LDPE with nanosize substances makes possible to use composition materials based on it more reliably. The research is significant from ecological, economical and energetic point of view.