Nowadays the increasing need in fast, effective and small diagnostic devices has triggered a new branch in the medicine – the point of care devices. The main idea of this concept is to make diagnosis an easy and available procedure. We decided to focus on the genetic diagnosis. Several SNPs associated to genes involved in different pathologies and organism responses to drugs were chosen. For example, a quick and simple test for the organism response to warfarin could be a very important asset for clinics and hospitals.  The goal of this project is to create a portable PCR device that will be easy-to-use, compact and efficient. The main point of creating such a chip is to reduce the time, the cost and the size of a PCR device. The chip will consist of two primary parts, the microfluidic channels on a polymer side and a ceramic part which will serve as a support. The microfluidic part of the chip will be made of PDMS (polydimethylsiloxane) and will incorporate a first capillary pump, an amplification/detection zone in the middle part of the chip and a second capillary pump. The liquid will be moved through the channel by capillary forces so there won’t be a necessity to use mechanical pumps. The second part of the chip will be used to stick the polymer and heat the liquid to the necessary temperature.  In order to make a simple construction we decided to use loop-mediated isothermal amplification method (LAMP). Unlike the classic PCR, the LAMP method uses an DNA polymerase enzyme which can perform the amplification at the temperature of 40°C so the circuit will not be divided in three different heat zones in order to preserve the conditions of a traditional PCR reaction.  The chip will give the possibility to accomplish amplification and also to detect single nucleotide polymorphisms or specific gene sequences. The detection can be performed in several ways: by fluorescence, by sedimentation depending the needs of the experiment. TaqMan or other fluorescent molecules can be used for detection. In this case, a fluorescence detector should be installed on the chip. It is also possible to use a coloration reaction in order to simplify the device, but it will be a less precise method.